Prognostic Value of Urinary Calprotectin, NGAL and KIM-1 in Chronic Kidney Disease

Conclusion: In contrast to the traditional biomarker “albuminuria”, neither the inflammatory biomarker calprotectin, nor the tubular biomarkers NGAL and KIM-1, provide robust prognostic information on the loss or renal function in a heterogeneous CKD population. All of them, however, are candidate prognostic biomarkers in primarily inflammatory re nal diseases.Kidney Blood Press Res 2018;43:1255 –1262
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research

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This article is to highlight the recommendations about blood pressure, cholesterol, and sugar control for ASCVD. Some medications that are beneficial for ASCVD were also reviewed. We hope the clinical outcomes of ASCVD can be improved in Taiwan through the implementation of these recommendations.
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
Publication date: Available online 18 May 2019Source: Canadian Journal of DiabetesAuthor(s): Robert SchlosserAbstractThe progressive natural history underlying type 2 diabetes often necessitates the use of multiple anti-hyperglycemic medications to achieve therapeutic goals and targets. The associated complexity of these regimens presents significant challenges to both physicians and patients. Fixed dose oral and fixed ratio injectable combination agents offer significant potential to simplify and consolidate therapy and lessen barriers to adherence.
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Our weekly series of diabetes humor at DiabetesMine features a cartoon by Jon Carter.
Source: Diabetes Mine - Category: Endocrinology Authors: Source Type: blogs
ConclusionsThis meta-analysis provides evidence for higher concentration of pro-inflammatory cytokines IFN-γ, IL-1β, IL-6, and TNF-α in autistic patents compared with control subjects. Also, meta-regression analyses point to the interaction of latitude, age, and gender with peripheral alterations of associated pro-inflammatory cytokines.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Publication date: Available online 18 May 2019Source: Journal of Clinical NeuroscienceAuthor(s): P. Bhogal, M. AlMatter, V. Hellstern, M. Aguilar Pérez, O. Ganslandt, H. Bäzner, H. HenkesAbstractAlthough mechanical thrombectomy (MT) has been shown in numerous trials to be a successful treatment option for patients with large vessel occlusion (LVO), there is limited information on the safety and effectiveness of the technique in cases of recurrent LVO. To this end, we performed a retrospective review of our prospectively maintained database to identify all patients that had undergone more than one MT procedure J...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
The review of nearly 19million people in the UK said those with diabetes should be monitored closely because of their raised risk of life-threatening liver disease.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
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Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
Authors: Bick I, Dowding D Abstract Nearly one million Medicare home health care beneficiaries are hospitalized annually of which one-quarter are considered preventable. Older hospitalized patients are at risk for nosocomial complications and poorer outcomes and incur higher health care costs. This paper reports the results of a systematic review of 28 studies on hospitalization risk factors of older home health care patients. It found that males, Blacks, and non-Asian minorities are at greater hospitalization risk. Factors associated with higher risk included skin ulcers, psychiatric conditions, dyspnea/COPD, card...
Source: Home Health Care Services Quarterly - Category: Nursing Tags: Home Health Care Serv Q Source Type: research
Publication date: Available online 18 May 2019Source: PeptidesAuthor(s): Allison B. Reiss, Daniel S. Glass, Eric Lam, Amy D. Glass, Joshua De Leon, Lora J. KasselmanAbstractCardiovascular disease (CVD) remains the leading cause of death worldwide, despite multiple treatment options. In addition to elevated lipid levels, oxidative stress and inflammation are key factors driving atherogenesis and CVD. New strategies are required to mitigate risk and most urgently for statin-intolerant patients. The neuropeptide hormone oxytocin, synthesized in the brain hypothalamus, is worthy of consideration as a CVD ancillary treatment be...
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Abstract Chronic kidney disease (CKD) includes all clinical features and complications during the progression of various kidney conditions towards end-stage renal disease (ESRD). These conditions include immune and inflammatory disease such as: primary and hepatitis C virus (HCV)-related glomerulonephritis; infectious disease such as pyelonephritis with or without reflux and tuberculosis; vascular disease such as chronic ischemic nephropathy; hereditary and congenital disease such as polycystic disease and congenital cystic dysplasia; metabolic disease including diabetes and hyperuricemia; and systemic disease (co...
Source: Journal of Nephrology - Category: Urology & Nephrology Authors: Tags: J Nephrol Source Type: research
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