Omega-3 fatty acids for mood disorders

Omega-3 fatty acids are found primarily in fish oil and certain marine algae. Because depression appears less common in nations where people eat large amounts of fish, scientists have investigated whether fish oils may prevent and/or treat depression and other mood disorders. Two omega-3 fatty acids — eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) — are thought to have the most potential to benefit people with mood disorders. How might omega-3s improve depression? Different mechanisms of action have been proposed. For example, omega-3s can easily travel through the brain cell membrane and interact with mood-related molecules inside the brain. They also have anti-inflammatory actions that may help relieve depression. More than 30 clinical trials have tested different omega-3 preparations in people with depression. Most studies have used omega-3s as add-on therapy for people who are taking prescription antidepressants with limited or no benefit. Fewer studies have examined omega-3 therapy alone. Clinical trials typically use EPA alone or a combination of EPA plus DHA, at doses from 0.5 to 1 gram per day to 6 to 10 grams per day. To give some perspective, 1 gram per day would correspond to eating three salmon meals per week. Meta-analyses (research that combines and analyzes results of multiple studies) generally suggest that the omega-3s are effective, but the findings are not unanimous because of variability between doses, ratios of EPA to DHA, and othe...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Anxiety and Depression Behavioral Health Drugs and Supplements Mental Health Source Type: blogs

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Source: Current Psychiatry Reviews - Category: Psychiatry Authors: Tags: Review article Source Type: research
Source: Current Psychiatry Reviews - Category: Psychiatry Authors: Tags: Review article Source Type: research
Publication date: Available online 13 December 2018Source: Seminars in Cell &Developmental BiologyAuthor(s): Talita Glaser, Vanessa Fernandes Arnaud Sampaio, Claudiana Lameu, Henning UlrichAbstractCalcium is the ubiquitous second messenger used by any living cell. The fine-tuning of intracellular free calcium concentration [(Ca2+)i] homeostasis and signalling pathways is crucial for the maintenance of the healthy organism. Many alterations in the homeostasis can be compensated by robust mechanisms; however, cells that already present some debility in those mechanisms, or that are over stimulated cannot compensate the s...
Source: Seminars in Cell and Developmental Biology - Category: Cytology Source Type: research
CONCLUSION: This study proposed alternate IVF adjustment factors that will produce more accurate screening results within the population of Ontario. PMID: 30539731 [PubMed - in process]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
CONCLUSION: Since the government of Ontario began funding IVF and ICSI cycles, more patients are accessing treatment, many for the first time. The clinical pregnancy rate was maintained, whereas multiple gestations were significantly reduced. These findings support the benefit of single embryo transfer in the context of funded IVF and ICSI and demonstrate the importance of government-funded assisted reproductive technology. PMID: 30528839 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
CONCLUSION: A literature search found 22 cases through PubMed and Ovid, with key words "amyotrophic lateral sclerosis" and "pregnancy." Both slow progression and rapid progression of ALS during pregnancy have been reported. Worsening of symptoms seems to be common, but little is still known about the influence of pregnancy on ALS onset and progression. PMID: 30528837 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
This study sought to determine students' needle handling efficacy and to examine the prevalence of formal training around needlestick safety and reporting procedures both nationally and, specifically, within the University of Toronto in Toronto, Ontario (U of T). A seven-question survey electronic survey was distributed to 116 undergraduate medical education (UME) leaders practising in high-risk rotations at 13 Canadian universities. Additionally, an eight-question survey was delivered electronically to 428 residents, fellows, and faculty in the Department of Obstetrics and Gynaecology at the U of T. A total of 34% of UME ...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
CONCLUSION: Observational studies suggest some degree of association between serum hormones measured in pregnancy and a woman's future risk of breast and ovarian cancer. More data are needed to determine sufficiently whether certain blood hormone levels measured in pregnancy are predictive of future cancer risk. PMID: 30528445 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
No 115 - Choc hémorragique. J Obstet Gynaecol Can. 2018 Dec;40(12):e883-e892 Authors: Martel MJ Abstract OBJECTIF: Passer en revue les aspects cliniques du choc hémorragique et formuler des recommandations pour son traitement. OPTIONS: La reconnaissance précoce du choc hémorragique et une intervention rapide et systématique aident à éviter des issues indésirables. RéSULTATS ATTENDUS: Formuler des directives cliniques pour aider à reconnaître rapidement le choc hémorragique et à pratiquer la réanimation ...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
Authors: Ladhani NNN, Fockler ME, Stephens L, Barrett JFR, Heazell AEP Abstract OBJECTIVE: The primary objective of this consensus statement is to develop consensus statements to guide clinical practice and recommendations for antenatal care, intrapartum care, and the psychosocial considerations necessary in the care of pregnant women with a history of stillbirth. INTENDED USERS: Clinicians involved in the obstetric management of women with a history of stillbirth or other causes of perinatal loss TARGET POPULATION: Women and families presenting for care following a pregnancy affected by stillbirth or other cau...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
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