Omega-3 fatty acids for mood disorders

Omega-3 fatty acids are found primarily in fish oil and certain marine algae. Because depression appears less common in nations where people eat large amounts of fish, scientists have investigated whether fish oils may prevent and/or treat depression and other mood disorders. Two omega-3 fatty acids — eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) — are thought to have the most potential to benefit people with mood disorders. How might omega-3s improve depression? Different mechanisms of action have been proposed. For example, omega-3s can easily travel through the brain cell membrane and interact with mood-related molecules inside the brain. They also have anti-inflammatory actions that may help relieve depression. More than 30 clinical trials have tested different omega-3 preparations in people with depression. Most studies have used omega-3s as add-on therapy for people who are taking prescription antidepressants with limited or no benefit. Fewer studies have examined omega-3 therapy alone. Clinical trials typically use EPA alone or a combination of EPA plus DHA, at doses from 0.5 to 1 gram per day to 6 to 10 grams per day. To give some perspective, 1 gram per day would correspond to eating three salmon meals per week. Meta-analyses (research that combines and analyzes results of multiple studies) generally suggest that the omega-3s are effective, but the findings are not unanimous because of variability between doses, ratios of EPA to DHA, and othe...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Anxiety and Depression Behavioral Health Drugs and Supplements Mental Health Source Type: blogs

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Publication date: Available online 30 May 2020Source: Life SciencesAuthor(s): Lakshmikripa Jagannathan, Emily Socks, Priya Balasubramanian, Robert McGowan, Thomas M. Herdt, Reza Kianian, Sheba M.J. MohanKumar, P.S. MohanKumar
Source: Life Sciences - Category: Biology Source Type: research
Publication date: August 2020Source: Fish &Shellfish Immunology, Volume 103Author(s): Young-Mao Chen, Chor Siong Tan, Ting-Yu Wang, Ching-Long Hwong, Tzong-Yueh Chen
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Suicide is a global health issue accounting for at least 800,000 deaths per annum. Numerous models have been proposed that differ in their emphasis on the role of psychological, social, psychiatric and neurobiological factors in explaining suicide risk. Ce...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news
This study aimed to investigate the risk factors for depressive symptoms among rural residents in Brazil. A representative sample of two hundred eighty-eight volunteers aged from 18 to 65  years was included and determining factors for high BDI-II score we...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Rural and Agricultural Issues Source Type: news
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Source: SafetyLit - Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news
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