Simvastatin improves cerebrovascular injury caused by ischemia ‑reperfusion through NF‑κB‑mediated apoptosis via MyD88/TRIF signaling.

In conclusion, simvastatin treatment may reduce I/R‑induced neuronal apoptosis via inhibition of the NF‑κB‑mediated MyD88/TRIF signaling pathway.
PMID: 30066928 [PubMed - as supplied by publisher]

Source: Molecular Medicine Reports - August 3, 2018 Category: Molecular Biology Tags: Mol Med Rep Source Type: research