A Postreconstruction Harmonization Method for Multicenter Radiomic Studies in PET

Conclusion: The proposed harmonization method is efficient at removing the multicenter effect for textural features and SUVs. The method is easy to use, retains biologic variations not related to a center effect, and does not require any feature recalculation. Such harmonization allows for multicenter studies and for external validation of radiomic models or cutoffs and should facilitate the use of radiomic models in clinical practice.

Source: Journal of Nuclear Medicine - August 2, 2018 Category: Nuclear Medicine Authors: Orlhac, F., Boughdad, S., Philippe, C., Stalla-Bourdillon, H., Nioche, C., Champion, L., Soussan, M., Frouin, F., Frouin, V., Buvat, I. Tags: Physics and Instrumentation Source Type: research