Molecular characteristics of colorectal cancer in a Middle Eastern population in a single institution

CONCLUSION: The RAS mutation rate was similar to Western and East Asian countries, but not for the BRAF mutation and MMR deficiency. We also found a prognostic effect for sex in the RAS wild-type group, a finding worthy of further exploration.  LIMITATIONS:Retrospective, single center and small sample size. Expression of MSH6 and PMS2 not analyzed. CONFLICT OF INTEREST:None. 
Source: Annals of Saudi Medicine - Category: General Medicine Tags: ISSUE 4 Source Type: research