Metabonomic Profiling Reveals Difference in Altered Metabolic Pathways Between Chronic Kidney Disease and High-Fat-Induced Insulin Resistance in Rats

Conclusion: Alterations in metabolites and relevant pathways were significantly different between the CKD- and HFD-induced IR rats. These findings may offer important information regarding the pathogenesis specific to IR caused by the decline in the renal function.Kidney Blood Press Res 2018;43:1199 –1211
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research