Crispr genome surgery in the retina in light of off-targeting

Conclusion: The CRISPR system has high potential to be an invaluable therapeutic tool as it has the ability to modify and repair pathogenic retinal lesions. Although it is not yet a perfect system, with further efforts to improve its specificity and efficacy along with careful screening of off-target mutations, CRISPR-mediated genome surgery potential can become maximized and applied to patients.
Source: RETINA - Category: Opthalmology Tags: Review Source Type: research