Aggressive polyfibromatosis with spontaneous keloid formation and erosive arthropathy

Polyfibromatosis is a rare syndrome in which patients may develop spontaneous keloid formation in association with penile, palmar, or plantar fibromatoses. Rare and aggressive forms of polyfibromatosis have been reported to cause erosive arthropathy. Here, we describe the case of a young man with spontaneous keloid formation and aggressive fibromatoses with erosive arthropathy resulting in amputation. A 23-year-old Caucasian man presented to our clinic with a history of multiple spontaneous keloids, contractures and nodules of the hands, and bilateral foot pain.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research