[ASAP] Identification of the 4-Position of 3-Alkynyl and 3-Heteroaromatic Substituted Pyridine Methanamines as a Key Modification Site Eliciting Increased Potency and Enhanced Selectivity for Cytochrome P-450 2A6 Inhibition

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.8b00084

Source: Journal of Medicinal Chemistry - August 1, 2018 Category: Chemistry Authors: Travis T. Denton, Pramod Srivastava, Zuping Xia, Gang Chen, Christy J. W. Watson, Alec Wynd, Philip Lazarus Source Type: research