Radiofrequency ablation compared with argon plasma coagulation after endoscopic resection of high-grade dysplasia or T1 adenocarcinoma in Barrett ’s esophagus: a randomized pilot study (BRIDE)

Endoscopic resection (ER) is safe and effective for Barrett ’s esophagus (BE) containing high-grade dysplasia (HGD) or mucosal adenocarcinoma (T1A); risk of metachronous neoplasia is reduced by ablation of residual BE using radiofrequency ablation (RFA) or argon plasma coagulation (APC). These have not been directly compared. We aimed to recruit up to 100 patients with BE and HGD or T1A confirmed by ER over 1 year in 6 centres in a randomized pilot study.

Source: Gastrointestinal Endoscopy - August 1, 2018 Category: Gastroenterology Authors: Mohammad Farhad Peerally, Pradeep Bhandari, Krish Ragunath, Hugh Barr, Rehan Haidry, Laurence Lovat, Howard Smart, Rebecca Harrison, Clive Stokes, Karen Smith, Tom Morris, John S. de Caestecker Source Type: research