Transcanal endoscopic infracochlear vestibular neurectomy: A pilot cadaveric study

ConclusionA transcanal, infracochlear approach to the IAC may permit a minimally invasive approach to distal vestibular neurectomy in cadavers with appropriate anatomy.
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research

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The pathology of Meniere ’s disease (MD) is well established to be endolymphatic hydrops. However, the mechanism underlying deafness and vertigo of MD or idiopathic endolymphatic hydrops is still unknown. In order to evaluate the pathogenesis of deafness and vertigo in MD, it seems to be rational to investigate the interr elationship between hydrops and inner ear disorders using animals with experimentally-induced endolymphatic hydrops. In spite of intense efforts by many researchers, the mechanism of vertiginous attack has been unexplained, because animals with experimental hydrops usually did not show vertiginous a ttack.
Source: Auris, Nasus, Larynx - Category: ENT & OMF Authors: Source Type: research
ConclusionOur study shows a reduced number of vertigo attacks and a positive effect on the discomfort generated by tinnitus and quality of life in patients with unilateral MD treated with SPC and when compared to patients treated with intravenous glycerol and dexamethasone. No effects on hearing thresholds were noted in both groups.
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research
Conclusions and significance: It is of great importance for intractable Meniere's disease to select surgically combined treatment process including Meniett, ESD and TSCO to effectively control the attacks of vertigo and a long-term follow-up. PMID: 31556757 [PubMed - as supplied by publisher]
Source: Acta Oto-Laryngologica - Category: ENT & OMF Authors: Tags: Acta Otolaryngol Source Type: research
ConclusionsLow-dose IT gentamicin administration based on clinical symptomatology can produce a satisfactory control of vertigo attacks after treatment; such protocol had an effect mainly on the vestibular function as demonstrated by the significant reduction in VOR gain in the affected side avoiding a cochlear damage.
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
Conclusion: Our findings indicate that deformation of subcellular organelles in the central portion of the VN is one of the key pathological indicators for the progressive severity and intractability of vertigo and support a vestibular nerve degeneration.
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Source: Journal of Neurology - Category: Neurology Source Type: research
Tone burst electrocochleography disproves a diagnosis of Meniere's disease treated aggressively. HNO. 2019 Aug 19;: Authors: Hornibrook J, Gourley J, Vraich G Abstract Reliable confirmation of the presence or absence of endolymphatic hydrops is essential to avoid confusing vestibular migraine with Meniere's disease. MRI inner ear imaging is a promising new method to confirm hydrops, avoiding both unnecessary invasive or destructive inner ear treatments, but it is not universally available. Tone burst electrocochleography is an older simple, quick, safe, and sensitive test that is potentially ...
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
Publication date: Available online 19 August 2019Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): Jenny X. Chen, Zizi Yu, Steven D. RauchMeniere's disease is characterized by idiopathic progressive fluctuating hearing loss, tinnitus, and episodic vertigo. Intratympanic gentamicin injection is the preferred therapeutic option for those who have failed conservative management including lifestyle modifications and oral medications. The procedure is simple and can be performed in the outpatient setting under local anesthesia with manageable recovery time. Patients may experience a disequilibrium s...
Source: Operative Techniques in Otolaryngology Head and Neck Surgery - Category: ENT & OMF Source Type: research
Publication date: Available online 5 August 2019Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): Danielle R. Trakimas, Steven D. Rauch, Aaron K. RemenschneiderTransmastoid labyrinthectomy is a highly effective procedure for controlling vertigo attacks in patients with refractory Meniere's disease and ipsilateral nonserviceable hearing. Performed under general anesthesia, the procedure involves a cortical mastoidectomy with subsequent opening and removal of the vestibular neuroepithelium of the 3 semicircular canal ampullae, as well as opening and ablation of the utricle and saccule of the vest...
Source: Operative Techniques in Otolaryngology Head and Neck Surgery - Category: ENT & OMF Source Type: research
Publication date: Available online 3 August 2019Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): Sarah E. Mowry, Mark Frilling, Nauman F. Manzoor, Maroun T. Semaan, Cliff A. MegerianEndolymphatic sac decompression and shunting is a nonablative surgical option for patients with intractable Meniere's disease. Sac surgery had a high success rate for vertigo control in this population with 75%-95% of patients experiencing improvement or resolution of their vertigo spells. The addition of high-dose steroid instillation into the sac has demonstrated improved vertigo rates. The risk of complications ...
Source: Operative Techniques in Otolaryngology Head and Neck Surgery - Category: ENT & OMF Source Type: research
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