Idiopathic, Infectious and Reactive Lesions of the Ear and Temporal Bone

AbstractA number of infectious, inflammatory and idiopathic lesions develop within otologic tissues that may share similar clinical and/or microscopic features. This review first provides a working classification for otitis externa, and then otitis media and includes two recently described entities, eosinophilic otitis media and otitis media with ANCA-associated vasculitis. Next, the microscopic findings of a spectrum of otopathologic conditions are described, including post-inflammatory conditions such as tympanosclerosis and aural polyps, an overview of animate aural foreign body as well as iatrogenic aural foreign body reactions. Finally, a review of fungal disease affecting the ear with a brief synopsis ofCandida auris, a recently described and virulent organism, is presented.
Source: Head and Neck Pathology - Category: Pathology Source Type: research

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Abstract Screening esophagogastroduodenoscopy of a 65-year-old man revealed a 4.7-cm polypoid in the gastric high body. Clinical and laboratory findings, including serum gastrin level (460 pg/mL) and biopsy findings, were consistent with a diagnosis of type I neuroendocrine tumor (NET). Histologically, the mass consisted of dilated tortuous glands at the surface and grade 1 NET in deeper tissue. Some hyperplastic glands exhibited a transition to adenocarcinoma, which invaded the NET, simulating a "tumor in tumor" appearance. Next-generation sequencing revealed that the adenocarcinoma component harbored a...
Source: Journal of Nippon Medical School - Category: Universities & Medical Training Authors: Tags: J Nippon Med Sch Source Type: research
Authors: López-Herrero F, Sánchez-Vicente JL, Espiñeira-Periñán MA, de Las Morenas-Iglesias J, Franco-Ruedas C, Rueda-Rueda T Abstract The case is presented of a 52-year-old woman with scleroderma, mixed connective tissue disease, and interstitial lung disease, who developed chronic cytomegalovirus necrotising retinitis while on treatment with prednisone, mycophenolate, and hydroxychloroquine. Initially diagnosed as macular hole, the patient underwent a pars plana vitrectomy. Two months after surgery, due to progressive worsening, the diagnosis was made and treatment started (intr...
Source: Archivos de la Sociedad Espanola de Oftalmologia - Category: Opthalmology Tags: Arch Soc Esp Oftalmol Source Type: research
New EverLift™ device designed to reduce costs and enhance complete polyp resections MECHANICSBURG, Pa., July 14, 2020 -- (Healthcare Sales &Marketing Network) -- GI Supply today announced the FDA clearance of EverLift™ Submucosal Lifting Agent , a new... Devices, Gastroenterology, FDA GI Supply, EverLift, Submucosal Lifting Agent
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
(Eindhoven University of Technology) Researchers at Eindhoven University of Technology developed a tiny plastic robot, made of responsive polymers, which moves under the influence of light and magnetism. In the future this 'wireless aquatic polyp' should be able to attract and capture contaminant particles from the surrounding liquid or pick up and transport cells for analysis in diagnostic devices. The researchers published their results in the journal PNAS.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
Publication date: July–August 2020Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 8, Issue 7Author(s): Guillaume Lefèvre, Amélie Leurs, Jean-Baptiste Gibier, Matthieu Groh, Jean-Emmanuel Kahn
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: July–August 2020Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 8, Issue 7Author(s): Mouhamad Nasser, Françoise Thivolet-Béjui, Vincent Cottin
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Kawasaki disease (KD) is an acute, self-limiting systemic vasculitis that predominately affects children. Neurological involvement is a known complication of KD, however, its association with KD severity remai...
Source: Pediatric Rheumatology - Category: Rheumatology Authors: Tags: Research article Source Type: research
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Source Type: research
AbstractPurpose of reviewTo provide an approach to the evaluation and management of primary and secondary inflammatory vasculitides affecting the central nervous system (CNS).Recent findingsAlthough early descriptions of inflammatory CNS vasculitis report a universally high mortality rate, more recent cohorts demonstrate that favorable outcomes rely on early diagnosis and treatment. New and re-purposed medications have shown promise in the treatment of CNS vasculitides, and novel imaging modalities may aid in diagnosis.SummaryA broad array of diseases can affect CNS vasculature. Accurate diagnosis of CNS vasculitides requi...
Source: Current Treatment Options in Cardiovascular Medicine - Category: Cardiology Source Type: research
The objective of this study was to assess the diagnostic accuracy of the immunochromatographic assay ‐based HpSA test in a male elderly cohort and identify factors affecting the accuracy. Data for asymptomatic elderly male citizens (≥65 years old) who received health checkups at the Chinese PLA General Hospital between July 2007 and November 2018 were collected. The diagnostic accuracy of the HpSA test was determined using the13C ‐urea breath test as a reference standard. Associations between baseline comorbidities and the accuracy of the HpSA test were analyzed. In total, 316 participants were enrolled, includ...
Source: MicrobiologyOpen - Category: Microbiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
More News: Otitis | Otitis Externa (Swimmer's Ear) | Otitis Media | Pathology | Polyps | Vasculitis