[ASAP] Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.8b00305

Source: Journal of Medicinal Chemistry - July 30, 2018 Category: Chemistry Authors: Clarissa G. Jakob, Anup K. Upadhyay, Pamela L. Donner, Emily Nicholl, Sadiya N. Addo, Wei Qiu, Christopher Ling, Sujatha M. Gopalakrishnan, Maricel Torrent, Steven P. Cepa, Jason Shanley, Alexander R. Shoemaker, Chaohong C. Sun, Anil Vasudevan, Kevin R. W Source Type: research