Fast food and asthma and allergy: Be afried, be deeply afried?

Respirology, EarlyView.
Source: Respirology - Category: Respiratory Medicine Authors: Source Type: research

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Publication date: Available online 19 February 2020Source: The LancetAuthor(s): Håvard Ove Skjerven, Eva Maria Rehbinder, Riyas Vettukattil, Marissa LeBlanc, Berit Granum, Guttorm Haugen, Gunilla Hedlin, Linn Landrø, Benjamin J Marsland, Knut Rudi, Kathrine Dønvold Sjøborg, Cilla Söderhäll, Anne Cathrine Staff, Kai-Håkon Carlsen, Anna Asarnoj, Karen Eline Stensby Bains, Oda C Lødrup Carlsen, Kim M Advocaat Endre, Peder Annæus Granlund, Johanne Uthus HermansenSummaryBackgroundSkin emollients applied during early infancy could prevent atopic dermatitis, and early comple...
Source: The Lancet - Category: General Medicine Source Type: research
Authors: Ingawale DK, Mandlik SK Abstract Inflammation is a physiological intrinsic host response to injury meant for removal of noxious stimuli and maintenance of homeostasis. It is a defensive body mechanism that involves immune cells, blood vessels and molecular mediators of inflammation. Glucocorticoids (GCs) are steroidal hormones responsible for regulation of homeostatic and metabolic functions of body. Synthetic GCs are the most useful anti-inflammatory drugs used for the treatment of chronic inflammatory diseases such as asthma, chronic obstructive pulmonary disease (COPD), allergies, multiple sclerosis, te...
Source: Immunopharmacology and Immunotoxicology - Category: Allergy & Immunology Tags: Immunopharmacol Immunotoxicol Source Type: research
ConclusionIgE polysensitization, to perennial and seasonal allergens, and levels of total IgE seem to be the main determinants of atopic multimorbidity in subjects with rhinitis. This indicates that disease-modifying treatment that targets IgE sensitization may be of value when decreasing the risk of developing atopic multimorbidity.
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research
Oral food challenges (OFC) play a vital role in the diagnosis of food allergy. History, skin prick testing (SPT), and serum specific IgE (sIgE) tests contribute to the probability assessment of having a food allergy, but do not allow for diagnostic certainty in confirming or de-labeling a food allergy.1 Accurate and cost-effective tests to diagnose food allergy are still required.2
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: CME Reviews Source Type: research
Thousands of US adults are killed by vaccine-preventable diseases each year,1 however, adult immunization rates in the US remain low, ranging from 8-64%.2 Increasing vaccination rates, and therefore preventing disease, requires an establishment of value by healthcare professionals and improved access to vaccinations.1 Allergists/immunologists should consider implementing routine vaccine administration for adolescents and adults into their practices. More than half of outpatient visits in the US are to specialists.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
In a transcription-wide association study of nasal epithelium, we identify novel and previously reported susceptibility genes for atopic asthma in children and show that gene co-expression networks differ markedly between children with and without atopic asthma.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
Stratification of asthmatic patients based on relevant biomarkers enables the prediction of responsiveness against immune-targeted therapies in patients with asthma. Individualised therapy in patients with eosinophilic asthma has yielded improved clinical outcomes; similar approaches in patients with neutrophilic asthma have yet to be developed. We determined whether colony-stimulating factors (CSFs) in the airway reflect the inflammatory phenotypes of asthma and contribute to disease progression of neutrophilic asthma. We analysed three different mouse models of asthma and assessed cytokine profiles in sputum from human p...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung biology and experimental studies, Asthma and allergy Original Articles: Asthma and basic science Source Type: research
Conclusions Exposures to oxidant air pollutants (O3 and NO2) but not PM2.5 were associated with an increased risk of incident asthma and eczema in children. This suggests that improving air quality may contribute to the prevention of asthma and other allergic disease in childhood and adolescence.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology, occupational and environmental lung disease, Asthma and allergy Original Articles: Asthma and pollution Source Type: research
Dietary antioxidant intake has been hypothesised to influence lung function. The association between total antioxidant capacity (TAC) of the diet at age 8 years and lung function development up to 16 years in 2307 participants from the Swedish population-based birth cohort BAMSE (Children, Allergy, Milieu, Stockholm, Epidemiology) was investigated. Information on TAC was obtained from a food frequency questionnaire at 8 years. Lung function was measured by spirometry at 8 and 16 years, impulse oscillometry (IOS) and exhaled nitric oxide fraction (FeNO) at 16 years. Low lung function was defined as ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Paediatric pulmonology Original Articles: Paediatrics Source Type: research
ConclusionsThese survey results suggest that the PLLR format was not known by a majority of prescribers and that the pregnancy letter category format is continuing to be used despite significant flaws in the old system. However, the survey did not address why prescribers were continuing to rely on the pregnancy letter category system. Whether this is due to the PLLR format itself or the lack of quality data to inform the safe use of medications in pregnancy cannot be determined from these survey results. FDA will use these survey results to refine the communication of pregnancy safety information in labeling and will expan...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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