Ultrasound Parameters for Human Osteoarthritic Subchondral Bone ex Vivo: Comparison with Micro-Computed Tomography Parameters

The aim of this study was to identify ultrasound parameters reflecting subchondral porosity (Po), subchondral plate thickness (Tpl) and bone volume fraction at the trabecular bone region (BV/TVTb). Sixteen osteoarthritic human lateral femoral condyles were evaluated ex vivo using a 15-MHz pulsed-echo ultrasound 3-D scanning system. The cartilage –subchondral bone (C-B) surface region (layer 1) and inner subchondral bone region (layer 2) were analyzed; we newly introduced entropy (ENT) and correlation (COR) of ultrasound texture parameters of the parallel (x) or perpendicular (z) direction to the C-B interface for this analysis.

Source: Ultrasound in Medicine and Biology - July 29, 2018 Category: Radiology Authors: Wataru Kiyan, Yasuaki Nakagawa, Akira Ito, Hirotaka Iijima, Kohei Nishitani, Momoko Tanima-Nagai, Shogo Mukai, Junichi Tajino, Shoki Yamaguchi, Akihiro Nakahata, Jue Zhang, Tomoki Aoyama, Hiroshi Kuroki Tags: Original Contribution Source Type: research