Functional neuroanatomy of peripheral inflammatory physiology: A meta-analysis of human neuroimaging studies
Publication date: Available online 29 July 2018Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Thomas E. Kraynak, Anna L. Marsland, Tor D. Wager, Peter J. GianarosAbstractCommunication between the brain and peripheral mediators of systemic inflammation is implicated in numerous psychological, behavioral, and physiological processes. Functional neuroimaging studies have identified brain regions that associate with peripheral inflammation in humans, yet there are open questions about the consistency, specificity, and network characteristics of these findings. The present systematic review provides a meta-analysis to address these questions. Multilevel kernel density analysis of 24 studies (37 statistical maps; 264 coordinates; 457 participants) revealed consistent effects in the amygdala, hippocampus, hypothalamus, striatum, insula, midbrain, and brainstem, as well as prefrontal and temporal cortices. Effects in some regions were specific to particular study designs and tasks. Spatial pattern analysis revealed significant overlap of reported effects with limbic, default mode, ventral attention, and corticostriatal networks, and co-activation analyses revealed functional ensembles encompassing the prefrontal cortex, insula, and midbrain/brainstem. Together, these results characterize brain regions and networks associated with peripheral inflammation in humans, and they provide a functional neuroanatomical reference point for future neuroimaging studies on brain-body in...
Publication date: Available online 3 June 2020Source: The Journal of Molecular DiagnosticsAuthor(s): Anthony N. Sireci, Jay L. Patel, Loren Joseph, Matthew C. Hiemenz, Oana C. Rosca, Samuel K. Caughron, Sarah A. Thibault-Sennett, Tara L. Burke, Dara L. Aisner
Publication date: Available online 2 June 2020Source: Pathology - Research and PracticeAuthor(s): Theodore Vougiouklakis, Brendan J. Belovarac, Andrew Lytle, Luis Chiriboga, Ugur Ozerdem
Publication date: Available online 2 June 2020Source: Pathology - Research and PracticeAuthor(s): Hyeongjoo Kim, Taewan Kim, Gunn Jaygal, Jongsoo Woo, Chang-Jin Kim, Moo-Jun Baek, Dongjun Jeong
Publication date: Available online 2 June 2020Source: Pathology - Research and PracticeAuthor(s): Qian Wu, Weiya Wang, Ping Zhou, Yiyun Fu, Ying Zhang, Yang W. Shao, Lili Jiang
Publication date: Available online 2 June 2020Source: The Journal of Foot and Ankle SurgeryAuthor(s): Sergio Agudiez Calvo, Jorge Ballesteros de Frutos, Héctor Raúl Cabezas García, Daniel Pecos Martin, Tomás Gallego Izquierdo
Publication date: Available online 2 June 2020Source: Orthopaedics &Traumatology: Surgery &ResearchAuthor(s): Alexandre Hardy, Guillaume Lefebvre
Publication date: Available online 2 June 2020Source: Journal of Orthopaedic TranslationAuthor(s): Zihao He, Linyang Chu, Xuqiang Liu, Xuequan Han, Kai Zhang, Mengning Yan, Xiaofeng Li, Zhifeng Yu
Publication date: Available online 3 June 2020Source: Journal of Clinical Orthopaedics and TraumaAuthor(s): Alaa A. Dawood
This study aims to assess whether older adults with low muscle mass or strength, in the presence of obesity, have an increased risk of knee (TKR) and hip replacement (THR) over 13 years. 1082 community-dwelling older adults (51% women; mean age 62.9 ± 7.5 years) were studied at baseline and multiple time points over 13 years. The incidence of TKR and THR was determined by data linkage to National Joint Replacement Registry. Appendicular lean and fat mass were measure d using DXA. Lower-limb muscle strength (LMS) was assessed by dynamometer. Low muscle mass and strength were defined as t...
Publication date: Available online 2 June 2020Source: Journal of OptometryAuthor(s): Tahereh Rakhshandadi, Mohamad-Reza Sedaghat, Farshad Askarizadeh, Hamed Momeni-Moghaddam, Mehdi Khabazkhoob, Abbasali Yekta, Foroozan Narooie-Noori