Fight Aging! Newsletter, July 30th 2018

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is published under the Creative Commons Attribution 4.0 International License. You are encouraged to republish and rewrite it in any way you see fit, the only requirements being that you provide attribution and a link to Fight Aging! To subscribe or unsubscribe please visit: https://www.fightaging.org/newsletter/ Contents Repair Biotechnologies is Hiring a Senior Research Scientist / Project Lead in New York State to Speed Work on the Treatment of Aging Oxidized Lipids Generated by Fat Tissue Lead to Inflammatory Macrophages Loss of Motility in Stem Cells may be Important in Tissue Aging The Role of Lipofuscin in Age-Related Neurodegenerative Disease New Evidence for Diminished Drainage of Cerebrospinal Fluid to be Important in Neurodegenerative Conditions Liz Parrish and BioViva, a Chapter in the Telomerase Gene Therapy Book B...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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Authors: Nieto-González JC, Serrano Benavente B, Molina Collada J PMID: 32739098 [PubMed - as supplied by publisher]
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Authors: Khan MY, Pandit S, Jayagopal PB, Oomman A, Chockalingam KC, Ramakrishnan A, Mane A, Mehta S, Shah S Abstract Background: Real-world data on the effectiveness of antihypertensive drugs (AHDs) in India is limited. The present study aims to provide updated evidence regarding the effectiveness of olmesartan as monotherapy or in combination with other AHDs in Indian patients with essential hypertension. Methods: Electronic medical record data of adult patients who were diagnosed with essential hypertension (≥140/90 mmHg) and were prescribed olmesartan as mono- or add-on therapy were retrospectively analy...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusions: This hospital-based registry shows that mildly symptomatic or asymptomatic young covid-19 patients have excellent prognosis. PMID: 32738843 [PubMed - as supplied by publisher]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
This study included 250 subjects with NAFLD and 500 non-NAFLD controls. Clinical, anthropological and biochemical data were collected. Subjects with body mass index (BMI)>= 25 kg/m2 were taken as obese and subjects with BMI
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusion: Patients with lower CD4 counts had significantly higher dysglycemia and IR. Serum testosterone levels were progressively lower (insignificant) with decreasing CD4 counts. PMID: 32738840 [PubMed - as supplied by publisher]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusion: Gastrointestinal side effects being most common side effect of metformin can lead to discontinuation of therapy. So before extensive evaluation of any GI problem in patient on metformin, other methods can be tried like temporary discontinuation, dose titration or proper intake of medicine. These side effects may also occur even after prolonged treatment with metformin. PMID: 32738838 [PubMed - as supplied by publisher]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusions: The results demonstrate that IV and oral levonadifloxacin therapy has excellent clinical activity against MRSA and offers advantage compared to other quinolones which generally lack MRSA coverage. Levonadifloxacin is safe and well tolerated in the treatment of ABSSSI caused by Gram -positive pathogens including MRSA as well as non-inferior to IV and oral linezolid, respectively. Similar pharmacokinetic profile of IV and oral levonadifloxacin provides an option for IV to oral switch for the treatment of subjects. Both oral and IV levonadifloxacin have recently been granted approval in India for the treatment of...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Gupta R, Pamecha H Abstract Objective: To find the serum hsCRP (high sensitive C reactive protein) levels in type 2 Diabetes Mellitus (DM) patients and compare its level between type 2 DM patients and healthy control subjects. To find the relationship of hsCRP levels in type 2 DM with and without vascular complications. To find the correlation of hsCRP with HbA1c and duration of type 2 DM among cases and to find the optimum cut-off value for hsCRP among type 2 DM patients. Methods: The study was conducted on type 2 DM patients with or without microvascular or macrovascular complications and nondiabetic...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Singh S, Lohakare AC Abstract Objective: Leptin levels are increased in obesity and have been found to be strongly associated with obesity, increased risk of cardiovascular diseases and morbidity. While, carotid intima-media thickness (CIMT) is measured to predict atherosclerosis in early phase. Thus, the objective of this study was to evaluate the leptin levels and CIMT in overweight and obese individuals. Methods: This cross-sectional study involving 95 subjects, was performed over a period of 1 year in the Department of Medicine, King George's Medical University, Lucknow. Anthropometric measurements...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Maydeo A, Patil G, Dalal A, Thakare S, Iyer A, Patil N Abstract Introduction: Endoscopic Sleeve gastroplasty (ESG) is a novel minimally invasive endoscopic restrictive bariatric procedure. We studied the safety, effectiveness, 6-month weight loss outcomes of ESG. Methods: We prospectively collected data for patients undergoing ESG at a tertiary care referral center. Laboratory investigations were performed preoperatively, and at 6 months post-operatively. Anthropometric measurements were noted pre and post-operatively at a frequency of 3 months for a 6-month follow-up. Patients with BMI ≥28 kg/m2 wh...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
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