Fight Aging! Newsletter, July 30th 2018

Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is published under the Creative Commons Attribution 4.0 International License. You are encouraged to republish and rewrite it in any way you see fit, the only requirements being that you provide attribution and a link to Fight Aging! To subscribe or unsubscribe please visit: https://www.fightaging.org/newsletter/ Contents Repair Biotechnologies is Hiring a Senior Research Scientist / Project Lead in New York State to Speed Work on the Treatment of Aging Oxidized Lipids Generated by Fat Tissue Lead to Inflammatory Macrophages Loss of Motility in Stem Cells may be Important in Tissue Aging The Role of Lipofuscin in Age-Related Neurodegenerative Disease New Evidence for Diminished Drainage of Cerebrospinal Fluid to be Important in Neurodegenerative Conditions Liz Parrish and BioViva, a Chapter in the Telomerase Gene Therapy Book B...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs

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We report on the use of a rhomboid flap for partial closure of a tracheal stoma. The rhomboid flap is a local flap that is frequently used by plastic surgeons because of its broad applications and not being very invasive. This is a low invasive and simple technique for partial closure of an excessively enlarged stoma.
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Publication date: Available online 16 September 2019Source: Academic RadiologyAuthor(s): Mohammad Hadi Bagheri, Holger Roth, William Kovacs, Jianhua Yao, Faraz Farhadi, Xiaobai Li, Ronald M. SummersPurposeAccurate pancreas segmentation has application in surgical planning, assessment of diabetes, and detection and analysis of pancreatic tumors. Factors that affect pancreas segmentation accuracy have not been previously reported. The purpose of this study is to identify technical and clinical factors that adversely affect the accuracy of pancreas segmentation on CT.Method and MaterialsIn this IRB and HIPAA compliant study, ...
Source: Academic Radiology - Category: Radiology Source Type: research
This article examines how CAM practitioners discuss vaccinations with parents in Switzerland, with a focus on childhood vaccinations and human papillomavirus (HPV) vaccinations. We describe how the CAM providers we interviewed (N = 17) and observed during vaccination consultations (N = 18 observations with 5 providers) employed individualized approaches to vaccination. Triangulation of qualitative evidence from interviews and observations allowed us to analyze their discourses and descriptions of experiences (i.e. what they said) and their practices in situ (i.e. what they did). Evidence gathered shows that practit...
Source: Social Science and Medicine - Category: Psychiatry & Psychology Source Type: research
Breast cancer in men is rare, but for those at a high risk, screening mammography may be beneficial in detecting early stage tumors.Medscape Medical News
Source: Medscape Radiology Headlines - Category: Radiology Tags: Hematology-Oncology News Source Type: news
ConclusionOur LncH19 ISH data verify the involvement of LncH19 in ESCC. Higher levels of LncH19 expression were not only detected in tumors with larger size and in clinical late stage, but also significantly associated with shorter survival, strongly indicating its clinical significance in the malignant progression of ESCC and useful value as a poor prognostic factor for the patients.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: Available online 16 September 2019Source: Pathology - Research and PracticeAuthor(s): Yu-Hui Zhou, Yang Liu, Wei Zhang, Chao Liu, Jian-Jun He, Xiao-Jiang TangABSTRACTBackgroundChemotherapy is the predominant treatment option for patients with breast cancer. Selection of patients according to biomarker will improve chemotherapy efficacy. In the present study, we examined the relations of the expression of candidate genes and 21-recurrence score (RS) results to patients’ demographic characteristics, histopathological factors, and outcomes.MethodsA total of 146 patients were enrolled in this study. The...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
ConclusionmiR-183-5p acts as a potential prognostic biomarker in gastric cancer and regulates cell functions by modulating EEF2.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: Available online 16 September 2019Source: Pathology - Research and PracticeAuthor(s): Kun Zhou, Huan Guo, Jun Zhang, Dongmei Zhao, Yuzhen Zhou, Zunrong Zheng, Yuhong Xu, Yanli Li, Donghua WangAbstractGastric cancer (GC) represents one of the most predominant malignancies with high incidence and mortality rates. Although traditional chemotherapeutics, including cisplatin are effective in the treatment of GC, patients often develop drug resistance in clinic. The present study aimed to explore the underlying mechanism of cisplatin-induced drug resistance in GC. The potential role of DNA demethylase ten-eleve...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: Available online 16 September 2019Source: Pathology - Research and PracticeAuthor(s): Ha Yoon Mo, Hyun Ji Son, Eun Ji Choi, Nam Jin Yoo, Chang Hyeok An, Sug Hyung Lee
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Publication date: Available online 16 September 2019Source: Orthopaedics &Traumatology: Surgery &ResearchAuthor(s): Christoph Hartog, Christoph Metzler, Christoph Meier, Fabian Kalberer, Peter WahlAbstractBackgroundBlood supply of the proximal metaphysis of the femur comes mainly from the lateral circumflex femoral artery (LCFA). Essentially, the anterior approach has gained popularity in hip surgery but routinely requires the ligation of the ascending branch of the LCFA. Until now, there is no study analysing the effect of previous hip surgery on the vascularization of the proximal femur. Notably, it might, howeve...
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
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