Clinical assessment and treatment of diabetes in patients with chronic kidney disease

Publication date: August–September 2018Source: Revista Clínica Española (English Edition), Volume 218, Issue 6Author(s): J. Carretero Gómez, J.C. Arévalo LoridoAbstractDiabetes mellitus type 2 is the main cause of chronic kidney disease. Patients with this disease have higher morbidity and mortality and risk of hypoglycaemia than those without this disease. In 2010, type 2 diabetes was the reason for starting renal replacement therapy in 24.7% of patients. The prevalence of microalbuminuria, proteinuria and a reduced glomerular filtration rate is 36%, 8% and 22%, respectively. The presence of albuminuria is a predictor of chronic kidney disease. Diabetic kidney disease, previously known as diabetic nephropathy, refers to kidney disease caused by diabetes. Renal hyperfiltration is a marker of intraglomerular hypertension and a risk factor for onset and progression. The new antidiabetic drugs, mainly dipeptidyl peptidase-4 inhibitors, sodium-glucose cotransporter inhibitors and glucagon-like peptide-1 agonists, have been shown to prevent or slow the progression of kidney disease.ResumenLa diabetes mellitus tipo 2 es la principal causa de enfermedad renal crónica. Estos pacientes presentan mayor morbimortalidad y riesgo de hipoglucemias que el resto. En 2010, la diabetes tipo 2 fue causa del inicio de terapia renal sustitutiva en el 24,7% de los pacientes. La prevalencia de microalbuminuria, proteinuria y disminución del ...
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research

Related Links:

(Reuters Health) - Workers with diabetes who switch to high-deductible health plans that require paying more out-of-pocket for care may be more likely than those who remain in low-deductible plans to delay needed checkups, a U.S. study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
When Alphabet’s Verily Lifesciences plunged into medtech the company took a deep dive. Some collaborations seemed futuristic and others were just natural. However, not all of the collaborations were going to be successful. And so, Verily, the former life sciences division of Google, along with Alcon, Novartis’ eyecare division, are putting the brakes on a plan for its smart lens to detect glucose levels. Brian Otis, PHD, Chief Technical Officer for Verily announced the news in a recent blog posting. “Our clinical work on the glucose-sensing lens demonstrated that there ...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Digital Health Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
TYPE 2 diabetes symptoms aren ’t easy to spot as they don’t necessarily make a person feel unwell. Needing to urinate more often can be one of the signs, but another is feeling itchy in a certain area of the body.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: February 2019Source: Biomedicine &Pharmacotherapy, Volume 110Author(s): Jannatul Mawa, Md. Atiar Rahman, M.A. Hashem, Md. Juwel HosenAbstractThis research investigated the functional food effect of Leea macrophylla (Roxb.) ex Hornem root extract on pancreatic necrosis in Streptozotocin-induced type-2 diabetes. Prior to animal intervention, Leea macrophylla root extract (LMR) was subjected to GC-MS analysis. Across a three-week intervention of fructose-fed albino model with LMR50, LMR100 and LMR200, the fluid &food intake, body weight changes, weekly blood glucose concentrations and oral glucose to...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
CHMP has issued a positive opinion on macimorelin, an oral ghrelin agonist, for use in the diagnosis of adult growth hormone deficiency.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Alert Source Type: news
HIGH blood pressure can lead to serious health complications if it ’s left untreated, but one way to prevent and control the condition is to eat a healthy and balanced diet. Pasta can form part of this diet, but you should avoid adding a certain ingredient during cooking.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Diabeloop, a company based in Grenoble, France, won the European CE Mark of approval for its DBLG1 blood sugar management system for type 1 diabetics. The system combines data gathered from a continuous blood glucose monitor and smart algorithms to d...
Source: Medgadget - Category: Medical Devices Authors: Tags: Medicine Pediatrics Source Type: blogs
Publication date: Available online 24 July 2018Source: Molecular Genetics and MetabolismAuthor(s): Meryl Waldman, Joan C. Han, Daniela P. Reyes-Capo, Joy Bryant, Kathryn A. Carson, Baris Turkbey, Peter Choyke, Jürgen K. Naggert, William A. Gahl, Jan D. Marshall, Meral Gunay-AygunAbstractAlström Syndrome is a ciliopathy associated with obesity, insulin resistance/type 2 diabetes mellitus, cardiomyopathy, retinal degeneration, hearing loss, progressive liver and kidney disease, and normal cognitive function. ALMS1, the protein defective in this disorder, localizes to the cytoskeleton, microtubule organizing center,...
Source: Molecular Genetics and Metabolism - Category: Genetics & Stem Cells Source Type: research
Abstract There is tremendous interest in the protein dipeptidyl peptidase 4 (DPP4) as a target in diabetes management and reduction of associated cardiovascular risk. The underlying reasons for this burgeoning interest are manifold. First, DPP4 inhibitor therapy in patients with Type 2 diabetes mellitus (T2DM) resulted in a reduction in proteinuria in the recently concluded "Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus - Thrombolysis in Myocardial Infarction 53" (SAVOR-TIMI 53) trial. Second, pharmacological as well as genetic inhibition of DPP4 has proven effec...
Source: Am J Physiol Renal P... - Category: Urology & Nephrology Authors: Tags: Am J Physiol Renal Physiol Source Type: research
More News: Chronic Kidney Disease | Diabetes | Diabetes Mellitus | Diabetes Type 2 | Endocrinology | Hypertension | Proteinuria | Sodium | Urology & Nephrology