Clustered DNA damage concentrated in particle trajectories causes persistent large-scale rearrangements in chromatin architecture.

CONCLUSION: Clustered damage concentrated in particle trajectories causes persistent rearrangements in chromatin architecture, which may affect structural and functional organization of cell nuclei.
PMID: 30049456 [PubMed - as supplied by publisher]

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - July 23, 2018 Category: Radiology Authors: Timm S, Lorat Y, Jakob B, Taucher-Scholz G, Rübe CE Tags: Radiother Oncol Source Type: research