Molecular profiling of regulatory T cells in pulmonary sarcoidosis.

CONCLUSION: Our findings offer a deeper insight into the molecular mechanisms of Tregs reduced suppression and increased apoptosis in patients with PS. Based on the current results, future studies should focus on possible therapeutic effect of TLR-2 signaling inhibition.
PMID: 30049532 [PubMed - as supplied by publisher]

Source: Journal of Autoimmunity - July 23, 2018 Category: Allergy & Immunology Authors: Kachamakova-Trojanowska N, Jazwa-Kusior A, Szade K, Kasper L, Soja J, Andrychiewicz A, Jakiela B, Plutecka H, Sanak M, Jozkowicz A, Sladek K, Dulak J Tags: J Autoimmun Source Type: research