Immunoglobulin G4-related sclerosing cholangitis.

Immunoglobulin G4-related sclerosing cholangitis.
Korean J Intern Med. 2018 Jul 27;:
Authors: Goodchild G, Pereira SP, Webster G
Abstract
Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibroinflammatory condition of which IgG4-related sclerosing cholangitis (IgG4-SC) is the biliary manifestation. In this review, we provide an overview of IgG4-RD, with a focus on the biliary manifestations. In particular, we describe the important differential diagnoses of IgG4-SC, namely, primary sclerosing cholangitis and cholangiocarcinoma, outline diagnostic criteria for IgG4-SC, provide insight into possible pathophysiological mechanisms underlying the disease and discuss short and long-term management options of this recently described disease.
PMID: 30045615 [PubMed - as supplied by publisher]

Source: The Korean Journal of Internal Medicine - July 27, 2018 Category: Internal Medicine Authors: Goodchild G, Pereira SP, Webster G Tags: Korean J Intern Med Source Type: research