Targeting Vascular Leakage for Novel Biomarker Diagnosis and Therapy of Severe Pulmonary Infections

Background: Persistent vascular leakage is a cardinal feature of major and severe infections, such as influenza and associated bacterial superinfections. These infections kill millions of individuals yearly, most commonly from complications affecting the vasculature such as acute respiratory distress syndrome and pulmonary edema. Newly emerged and re-emerging infections that threaten public health globally, such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and Ebola fever, also involve vascular leakage as an important factor of morbidity and mortality.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: UMP. 012 Source Type: research