Screening for viral proteins to some emerging viruses in African straw-coloured fruit bats (Eidolon Helvum) captured in Zaria, Nigeria

This study was carried out to screen for the presence antibodies to Nipah virus soluble G protein (NiV sG), Nipah virus N protein (NiVN), Nipah virus soluble F protein (NiV sF), Hendra virus soluble G protein (HeV sG), Zaire Ebola virus G protein (EboV G), Cedar virus soluble G protein (CedV sG) and Menangle virus N protein (MenVN) in Eidolon helvum captured in Zaria, Nigeria.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: UMP. 232 Source Type: research

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Publication date: Available online 15 July 2019Source: Trends in GeneticsAuthor(s): René M. Marsano, Ennio Giordano, Giovanni Messina, Patrizio DimitriConstitutive heterochromatin represents a significant portion of eukaryotic genomes, but its functions still need to be elucidated. Even in the most updated genetics and molecular biology textbooks, constitutive heterochromatin is portrayed mainly as the ‘silent’ component of eukaryotic genomes. However, there may be more complexity to the relationship between heterochromatin and gene expression. In the fruit fly Drosophila melanogaster, a model for hetero...
Source: Trends in Genetics - Category: Genetics & Stem Cells Source Type: research
Publication date: 30 November 2019Source: Food Chemistry, Volume 299Author(s): Shao-jia Li, Xiu-lan Xie, Sheng-chao Liu, Kun-song Chen, Xue-ren YinAbstractCitrus fruit postharvest degreening is a critical stage in marketing, carried out by exposure to ethylene or ethephon. Genome-wide screening of the AP2/ERF superfamily indicated that a novel ERF-II (CitERF6) was shown to trans-activate the CitPPH promoter. Expression of CitERF6 is associated with both developmental and postharvest degreening in citrus fruit. Transient and stable over-expression of CitERF6 in Nicotiana tabacum leaves and ‘Ponkan’ fruit also re...
Source: Food Chemistry - Category: Food Science Source Type: research
Publication date: Available online 16 July 2019Source: Food ChemistryAuthor(s): S.T. Narenderan, S.N. Meyyanathan, Veera Venkata Satyanarayana Reddy Karri, B. Babu, Pavankumar ChintamaneniAbstractAn effective, simple and sensitive analytical method has been developed employing liquid chromatography coupled with tandem mass spectrometry and validated for estimation of five organophosphate pesticides at trace levels in six fruits and twelve vegetables. Plackett-Burman design and central composite design was used to screen and optimize the significant factors in modified QuEChERS (quick, easy, cheap, effective, rugged and saf...
Source: Food Chemistry - Category: Food Science Source Type: research
In this study, the native carotenoid profiles of mandarin and orange juices were studied. Xanthophylls in oranges were esterified with lauric, myristic, palmitic and stearic acids. The fatty acids esterifying β-cryptoxanthin in mandarins were lauric, myristic, palmitic and capric acid. In oranges, the average relationships of total free carotenoids to the sum of mono-esters and di-esters were 0.82 and 1.67, respectively, and the average relationships total mono-esters to total of di-esters was 2.51. In general, the mono-ester fraction was the most significant quantitatively. In mandarins, the average relationship of t...
Source: Food Chemistry - Category: Food Science Source Type: research
This study demonstrates a new approach for multi-elemental analysis in fruit wine with great convenience and high accuracy.
Source: Food Chemistry - Category: Food Science Source Type: research
This study reports a clear-cut relationship of the technological use of specific filter aids with highly variable vanadium levels in beer, wine, and fruit juices. First, the previously reported broad range of vanadium levels was confirmed in 68 commercial beverages by ICP-MS. Since cloudy apple juices exhibited significantly lower vanadium amounts than clear apple juices, filter aids used for clarification were analyzed and found to contain substantial and highly variable amounts of vanadium, particularly in all analyzed diatomite (38-368 mg vanadium per kg filter aid), but not in perlite products (
Source: Food Chemistry - Category: Food Science Source Type: research
Publication date: Available online 15 July 2019Source: International Journal for Parasitology: Parasites and WildlifeAuthor(s): Cora Delling, Denny Böttcher, Vivien Schiffbauer, Andreas Bernhard, Ronald SchmäschkeAbstractThe cestode Taenia crassiceps parasitizes in the intestine of domestic and wild carnivores, especially in red foxes. Usually, the metacestode stage, also known as Cysticercus longicollis, is located in muscles, peritoneal and pleural cavity of wild rodents. In this case, larval stages were found in a female Cape fur seal, which lived in a German zoo since June 1998. In January 2019, the animal pr...
Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
In this study, we evaluated the antiviral activity of the nucleoside analog 4′-azidocytidine (4′N3-C, R1479) and its 2′-monofluoro- and 2′-difluoro-modified analogs (2′F-4′N3-C and 2′diF-4′N3-C) against representative paramyxoviruses (Nipah virus, Hendra virus, measles virus, and human parainfluenza virus 3) and filoviruses (Ebola virus, Sudan virus, and Ravn virus). We observed enhanced antiviral activity against paramyxoviruses with both 2′diF-4′N3-C and 2′F-4′N3-C compared to R1479. On the other hand, while R1479 and 2′diF-4′N3-C inhibit...
Source: Antiviral Therapy - Category: Virology Source Type: research
In this study, we evaluated the antiviral activity of the nucleoside analog 4'-azidocytidine (4'N3-C, R1479) and its 2'-monofluoro- and 2'-difluoro-modified analogs (2'F-4'N3-C and 2'diF-4'N3-C) against representative paramyxoviruses (Nipah virus, Hendra virus, measles virus, and human parainfluenza virus 3) and filoviruses (Ebola virus, Sudan virus, and Ravn virus). We observed enhanced antiviral activity against paramyxoviruses with both 2'diF-4'N3-C and 2'F-4'N3-C compared to R1479. On the other hand, while R1479 and 2'diF-4'N3-C inhibited filoviruses similarly to paramyxoviruses, we observed 10-fold lower filovirus inh...
Source: Antiviral Research - Category: Virology Authors: Tags: Antiviral Res Source Type: research
by Raina K. Plowright, Alison J. Peel, Daniel G. Streicker, Amy T. Gilbert, Hamish McCallum, James Wood, Michelle L. Baker, Olivier Restif Progress in combatting zoonoses that emerge from wildlife is often constrained by limited knowledge of the biology of pathogens within reservoir hosts. We focus on the host–pathogen dynamics of four emerging viruses associated with bats: Hendra, Nipah, Ebola, and Marburg viruses. Spillover of ba t infections to humans and domestic animals often coincides with pulses of viral excretion within bat populations, but the mechanisms driving such pulses are unclear. Three hypotheses dom...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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