A new biomarker for diagnosis and monitoring of effectiveness of therapy of Brucellosis

Background: Brucellosis is an important zoonotic disease causing huge economic losses to livestock industry and human sufferings worldwide. Current treatment of bovine Brucellosis is ineffective and infected animals become carriers. Brucella abortus Strains S19, producing antibody alone and RB51, inducing cell mediated immunity only, are used as live attenuated vaccines. However, antibody alone is ineffective for the intracellular pathogen and RB51 is Rifampicin resistant. Both strains can infect humans and cause abortions in animals.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: UMP. 826 Source Type: research