Betaine reduces β-amyloid-induced paralysis through activation of cystathionine-β-synthase in an Alzheimer model of Caenorhabditis elegans

ConclusionOur studies show that betaine is able to reduce homocysteine levels and β-amyloid-induced toxicity in aC. elegans model for Alzheimer ’s disease. This effect is independent of the remethylation pathway but requires the transsulfuration pathway mediated by cystathionine-β-synthase.

http://link.springer.com/10.1186/s12263-018-0611-9

Source: Genes and Nutrition - July 27, 2018 Category: Nutrition Source Type: research