The antibiotic resistome: what's new?

The antibiotic resistome: what's new?
Curr Opin Microbiol. 2014 Sep 30;21C:45-50
Authors: Perry JA, Westman EL, Wright GD
Abstract
The antibiotic resistome is dynamic and ever expanding, yet its foundations were laid long before the introduction of antibiotics into clinical practice. Here, we revisit our theoretical framework for the resistome concept and consider the many factors that influence the evolution of novel resistance genes, the spread of mobile resistance elements, and the ramifications of these processes for clinical practice. Observing the trends and prevalence of genes within the antibiotic resistome is key to maintaining the efficacy of antibiotics in the clinic.
PMID: 25280222 [PubMed - as supplied by publisher]

Source: Current Opinion in Microbiology - September 30, 2014 Category: Microbiology Authors: Perry JA, Westman EL, Wright GD Tags: Curr Opin Microbiol Source Type: research