Mixed Results with MRI for Liver Triglycerides in NAFLD (CME/CE)

(MedPage Today) -- Proton density fat fraction MRI correlated with steatosis grade; suboptimal for advanced fibrosis
Source: MedPage Today Primary Care - Category: Primary Care Source Type: news

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This study analyzed 15 randomized, controlled trials involving 782 patients with NAFLD. Probiotics and synbiotics supplementation could significantly improve liver steatosis, alanine aminotransferase, aspartate aminotransferase, triglyceride, total cholesterol, high-density lipoprotein, low-density lipoprotein, homeostasis model assessment-insulin resistance, liver stiffness and tumor necrosis factor-alpha (allP  
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
Authors: Li AA, Ahmed A, Kim D Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and encompasses a spectrum of pathology from simple steatosis to inflammation and significant fibrosis that leads to cirrhosis. NAFLD and its comorbid conditions extend well beyond the liver. It is a multisystemic clinical disease entity with extrahepatic manifestations such as cardiovascular disease, type 2 diabetes, chronic kidney disease, hypothyroidism, polycystic ovarian syndrome, and psoriasis. Indeed, the most common causes of mortality in subjects with NAFLD are cardiovascular disease, f...
Source: Gut and Liver - Category: Gastroenterology Tags: Gut Liver Source Type: research
ConclusionIn individuals with diabetes and NAFLD, PNPLA3 gene rs738409 C>G polymorphism is a risk marker for significant liver fibrosis and cardiovascular disease and may be associated with better glycemic control.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Source: Journal of Hepatology - Category: Gastroenterology Source Type: research
Conditions:   Nonalcoholic Fatty Liver;   Metabolic Syndrome Intervention:   Sponsor:   Hippocration General Hospital Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: The immunohistochemical expression of TGF-β1 may be complementary to routine methods of liver fibrosis evaluation. PMID: 31187872 [PubMed - as supplied by publisher]
Source: Folia Histochemica et Cytobiologica - Category: Cytology Tags: Folia Histochem Cytobiol Source Type: research
Genetic factors may impact non-alcoholic fatty liver disease (NAFLD) severity. We aimed to assess the prevalence of patatin-like phospholipase domain-containing 3 protein (PNPLA3) gene rs738409 C>G polymorphism in Brazilian type 2 diabetes individuals and to investigate its association with liver disease severity, diabetic chronic degenerative complications and metabolic control.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - Category: Nutrition Authors: Source Type: research
This article reviews studies of the target mechanisms of herbal treatments for insulin resistance.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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Source: Molecular Nutrition and Food Research - Category: Food Science Authors: Tags: Review Source Type: research
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
More News: Liver | Non-alcoholic Fatty Liver Diseases (NAFLD) | Primary Care | Urology & Nephrology