Cutting-Edge Primary Care Data From DDW 2018 Cutting-Edge Primary Care Data From DDW 2018

Dr David Johnson shares new results impacting colon cancer screening, diabetes, anti-TNF agents, and other key areas.Medscape Gastroenterology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Gastroenterology Commentary Source Type: news

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AbstractChronic exposure to inorganic arsenic (As) —As(III) + As(V)—is associated with type 2 diabetes, vascular diseases and various types of cancer. Although the oral route is the main way of exposure to inorganic As, the adverse gastrointestinal effects produced by chronic exposure are not well documented. The aim of the present study is to evaluate the effect of chronic exposure to As(III) on the intestinal epithelium. For this purpose, NCM460 cells, non‐transformed epithelial cells from the human colon, were exposed to As(III) (0.01‐0.2 mg/L) for 6 months and monitored for acquisiti...
Source: Journal of Applied Toxicology - Category: Toxicology Authors: Tags: RESEARCH ARTICLE Source Type: research
Conclusions: Patients with Interval cancer tend to be older and have diabetes. These patient groups should be more carefully or more frequently screened for pre-malignant lesions.Dig Dis
Source: Digestive Diseases - Category: Gastroenterology Source Type: research
This study aimed to quantify health and health-related economic impacts associated with physical activity in an urban riverside park regeneration project in Barcelona, Spain. We used data from Barcelona local authorities and meta-analysis assessing physical activity and health outcomes to develop and apply the “Blue Active Tool”. We estimated park user health impacts in terms of all-cause mortality, morbidity (ischemic heart disease; ischemic stroke; type 2 diabetes; cancers of the colon and breast; and dementia), disability-adjusted life years (DALYs) and health-related economic impacts. We estimated t...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
MONDAY, Feb. 4, 2019 -- Research consistently tells you just how important exercise is for health. It can help head off heart disease, stroke, diabetes and many types of cancer, including breast and colon cancers. A report published in the New...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
. It saddens me: As popular as the Wheat Belly books and lifestyle have been, there are still millions of people who say things like “Oh, that Wheat Belly thing is just about being gluten-free.” They couldn’t be more wrong and have clearly not read any of the books. Yes, you can be gluten-free and consume foods that naturally have no gluten, gliadin, wheat germ agglutinin, amylopectin A, phytates, and the rest of the toxic components contained in wheat and related grains. You can eat apples, bacon, eggs, and salmon that are naturally gluten-free. You can drink water or tea that is gluten-free. No problems...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates gluten gluten-free grain-free grains wheat belly Source Type: blogs
Join us Wednesday evening, February 6th, at 8 pm EST/ 7 pm CST/6 pm MT/5 pm PT for my Undoctored SIBO Workshop: A 2-hour in-depth exploration of SIBO that I shall present via live video broadcast. The cost to attend is $55. (I will also be giving a SIBO Workshop for Undoctored Inner Circle members on Tuesday, February 5th at the same time slot.) An unprecedented number of people now have small intestinal bacterial overgrowth, SIBO, an intestinal condition that has reached epidemic proportions. SIBO causes or worsens numerous health conditions such as fibromyalgia, irritable bowel syndrome, ulcerative colitis, and...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates bowel flora Inflammation microbiota probiotic silo small intestinal bacterial overgrowth undoctored Source Type: blogs
In this study, we show that calorie restriction is protective against age-related increases in senescence and microglia activation and pro-inflammatory cytokine expression in an animal model of aging. Further, these protective effects mitigated age-related decline in neuroblast and neuronal production, and enhanced olfactory memory performance, a behavioral index of neurogenesis in the SVZ. Our results support the concept that calorie restriction might be an effective anti-aging intervention in the context of healthy brain aging. Greater Modest Activity in Late Life Correlates with Lower Incidence of Dementia ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
We describe the epidemiologic shifts of CRC incidence and mortality across age groups as well as the differences in clinicopathologic, molecular, treatment, and survival characteristics between young and older patients. Novel studies of the microbiome may elucidate bacterial causes of CRC carcinogenesis in younger individuals. Moving up the colonoscopy screening to age 45 in normal-risk individuals should prove beneficial in detecting more patients with early-onset CRC.SummaryWe favor the development of risk-adaptive screening decision algorithms and flexible sigmoidoscopy screening at age 40 given the predilection for lef...
Source: Current Oncology Reports - Category: Cancer & Oncology Source Type: research
Contributors : Pablo Minguez ; Laura Del Puerto-NevadoSeries Type : Expression profiling by arrayOrganism : Homo sapiensThis is a transcriptomics analysis contributing to a bigger project that tries to shed light on the role of type 2 diabetes mellitus (T2DM) as a risk factor for colon cancer (CC). Here we present a gene expression screening of 7 colon tumor xenograft samples, 2 with diabetic mice and 5 with normal blood glucose levels. For xenograft model details see: Prieto I, et al. (2017) Colon cancer modulation by a diabetic environment: A single institutional experience. PLoS One 12(3):e0172300
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
In conclusion, diabetes is associated to deregulation of cancer-related processes in normal colon mucosa adjacent to tissue which has undergone a malignant transformation. These data support the existence of the field of cancerization paradigm in diabetes and set a new framework to study link between diabetes and cancer.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
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