Decrease of 5-hydroxymethylcytosine and TET1 with nuclear exclusion of TET2 in small intestinal neuroendocrine tumors

Small intestinal neuroendocrine tumors (SI-NETs) originate from enterochromaffin cells scattered in the intestinal mucosa of the ileum and jejunum. Loss of one copy of chromosome 18 is the most frequent observ...

Source: BMC Cancer - July 25, 2018 Category: Cancer & Oncology Authors: Elham Barazeghi, Surendra Prabhawa, Olov Norl én, Per Hellman, Peter Stålberg and Gunnar Westin Tags: Research article Source Type: research