Effect of Apolipoprotein E ɛ4 Carrier Status on Cognitive Response to Acetylcholinesterase Inhibitors in Patients with Alzheimer's Disease: A Systematic Review and Meta-Analysis.

CONCLUSIONS: APOE ɛ4 carrier status had no significant influence on the treatment response to AChEIs in patients with AD. AChEIs had a positive therapeutic effect compared with placebo regardless of APOE ε4 carrier status. PMID: 30041236 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30041236?dopt=Abstract

Source: Dementia and Geriatric Cognitive Disorders - July 25, 2018 Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research