The value of the 24-h proteinuria in evaluating the severity of preeclampsia and predicting its adverse maternal outcomes.

The value of the 24-h proteinuria in evaluating the severity of preeclampsia and predicting its adverse maternal outcomes. Hypertens Pregnancy. 2018 Jul 24;:1-8 Authors: Li B, Lin L, Yang H, Zhu Y, Wei Y, Li X, Chen D, Zhao X, Cui S, Ding H, Ding G, Meng H, Wei H, Sun X, Xin H Abstract BACKGROUND: To identify the 24-h proteinuria value with quantitative analysis and how it correlates with the severity of preeclampsia and subsequent adverse maternal outcomes in the Chinese population. STUDY DESIGN: Eleven hospitals in 10 provinces across China were chosen, in which 1,738 pregnant women complicated by hypertensive disorders of pregnancy (HDP) with the records of 24 h proteinuria were enrolled. They were allocated into four groups: patients with maximal quantified proteinuria
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research

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AbstractPreeclampsia, a major disorder of human pregnancy, manifests as persistent hypertension and proteinuria presenting after 20  weeks of pregnancy. Multiple systemic symptoms might be associated with preeclampsia including thrombocytopenia, liver impairment, pulmonary edema, and cerebral disturbances. However, vascular dysfunction remains the core pathological driver of preeclampsia. Defective placental implantation follow ed by dysfunctional placental spiral artery development promotes a hypoxic environment. Massive endothelial dysfunction characterized by reduced vasodilation, augmented vasoconstriction, and in...
Source: Microcirculation - Category: Research Authors: Tags: INVITED REVIEW Source Type: research
​BY GREGORY TAYLOR, DO, &SHERIF G. EL-ALAYLI, DOA 30-year-old G5P3 presented to the ED with bilateral lower-extremity edema and headache for three days. She presented one week after an uncomplicated full-term vaginal delivery with an unremarkable pregnancy course and no prior requirement for antihypertensive therapy. The headache was described as achy to sharp, with associated photophobia. She also noted occasional vaginal spotting, which was common a few weeks after delivery. She denied any chest pain, shortness of breath, nausea or vomiting, abdominal pain, or any other symptoms. She admitted to occasional mild cra...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
We report of a patient who presented with enteritis as manifestation of new-onset SLE during the first trimester of pregnancy. Patients concerns: The 23-year nulliparous patient was admitted to a district hospital with abdominal pain, nausea, vomiting and bloody diarrhea at a gestational age (GA) of 10 weeks. Her symptoms improved with symptomatic treatment and she was discharged a few days later. At 15 weeks’ of gestation she was readmitted. Her lab results revealed mild anemia and thrombocytopenia. Ascites, renal failure and proteinuria developed. An infectious cause was suspected, but stool samples and urine cu...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Publication date: July 2017 Source:Hospital Medicine Clinics, Volume 6, Issue 3 Author(s): Christine M. CombsTeaser Preeclampsia is a multisystem disorder of new-onset hypertension in the second half of pregnancy associated with abnormalities in several organ systems. Manifestations of maternal vascular endothelial dysfunction include proteinuria, thrombocytopenia, microangiopathic hemolysis, pulmonary edema, hepatic ischemia, hypercoagulability, stroke, and seizure. Preeclampsia is common, with a worldwide prevalence of 2% to 8%, and 3% to 5% of all US pregnancies, with prevalence in primiparous pregnancies approximately...
Source: Hospital Medicine Clinics - Category: Internal Medicine Source Type: research
Conclusion Pregnancy outcomes were unfavorable in both the PE without proteinuria and PE with proteinuria groups. Women with non-PE uncontrolled hypertension also had poor pregnancy outcomes, although their outcomes were better than those of women with PE.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: Available online 12 December 2016 Source:Anesthesiology Clinics Author(s): Nerlyne K. Dhariwal, Grant C. LyndeTeaser Hypertensive disorders of pregnancy complicate approximately 10% of all deliveries in the United States and are a leading cause of maternal and fetal morbidity and mortality. Preeclampsia is defined as hypertension in association with proteinuria, thrombocytopenia, impaired liver function, renal insufficiency, pulmonary edema, or new-onset cerebral or visual disturbances. The greatest risk factor for the development of preeclampsia is a history of preeclampsia. There currently is no effect...
Source: Anesthesiology Clinics - Category: Anesthesiology Source Type: research
Preeclampsia (PE) is a devastating disorder of pregnancy that affects up to 8% of pregnant women in the United States. The diagnosis of PE is made by the presentation of new-onset hypertension, ≥140 mmHg systolic blood pressure (BP) or ≥90 mmHg diastolic BP, and either proteinuria or another accompanying sign/symptom, such as renal insufficiency, thrombocytopenia, hepatic dysfunction, pulmonary edema, or cerebral/visual. These signs can occur suddenly and without warning. PE that presents before 34 wk of gestation is considered early onset and carries a greater risk for perinatal morbidity/mortality than late-onset P...
Source: Physiological Genomics - Category: Genetics & Stem Cells Authors: Tags: Call for Papers: Systems Biology and Polygenic Traits Source Type: research
Conditions:   Preeclampsia;   Hypertension;   Proteinuria;   Thrombocytopenia;   Renal Insufficiency;   Impaired Liver Function;   Pulmonary EdemaIntervention:   Sponsor:   Progenity, Inc.Recruiting - verified May 2016
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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