DEET Is the Most Effective Bug Spray. But Is It Safe?

Sure, itchy bug bites are a nuisance. But for those living in parts of the country where mosquito or tick-borne illnesses are common—and these days, that’s most of us—bug-repellent sprays and liquids are an important safeguard against Lyme disease, West Nile virus and other serious health conditions. The annual number of people sickened by mosquitos or tick bites has more than tripled since 2004, according to the CDC. The World Health Organization has concluded that climate change is a likely contributor to these increases, which are predicted to continue as warmer global temperatures expand the habitats of mosquitos, ticks and other disease-spreading bugs. For all of these reasons, more and more people are looking for safe and effective ways to keep biting bugs at bay. And a 2002 New England Journal of Medicine study concluded that the chemical N,N-diethyl-m-toluamide—more commonly known as DEET—is among the most effective ways to prevent bites. “I use DEET all the time when I’m working in the field,” says Jonathan Day, a professor of medical entomology at the University of Florida. DEET seems to work by binding to CO2 receptors in the nose-like appendage a mosquito uses to probe a person’s skin for blood, Day says. Rather than kill the mosquito, DEET somehow blocks the insect’s ability to feed. “It works on contact—not on smell—so mosquitos will still land on you but they won’t bite,”...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime Research Source Type: news

Related Links:

In this study, after bioinformatics analysis and lncRNA identification, the expression of two lncRNAs including NONHSAT139215 and NONHSAT139219 was investigated among the blood samples of severe hemophilia A and healthy (non-hemophilia) subjects using the relative qRT-PCR technique. RESULTS: The melting curve analysis confirmed the specificity of primers. Also, the standard curve showed that the efficiency of reactions for β2-microglobulin (B2M), NONHSAT139215 and NONHSAT139219 was 1.91, 1.96 and 2.01, respectively. On the other hand, the statistical analysis using REST software indicated that the expression of NO...
Source: Hematology - Category: Hematology Tags: Hematology Source Type: research
Authors: Kim TH, Kim SY, Tang A, Lee JM Abstract The goal of this review is to present the similarities and differences among the latest guidelines for noninvasive diagnosis of hepatocellular carcinoma (HCC) of American Association for the Study of Liver Disease (AASLD), European Association for the Study of the Liver (EASL), Liver Imaging Reporting and Data System (LI-RADS), Asian Pacific Association for the Study of the Liver (APASL), and Korean Liver Cancer Association- National Cancer Center (KLCA-NCC) of Korea. In 2018, major guideline updates have been proposed by the AASLD, EASL and KLCA-NCC; AASLD newly inc...
Source: Clinical and molecular hepatology - Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research
Authors: Liang LY, Wong GL Abstract Despite all these exciting developments, there remain some unmet needs in the management for patients with chronic hepatitis B (CHB). As majority of CHB patients are going to use oral nucleos(t)ide analogues (NAs) for decades, Safety profile of NAs is of no doubt an important issue. The newest nucleotide analogue tenofovir alafenamide is potent in terms of viral suppression, together with favourable renal and bone safety profile. Biochemical response as reflected by alanine aminotransferase (ALT) normalization is recently found to be prognostically important. Patients who achieve...
Source: Clinical and molecular hepatology - Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research
Authors: Abe K, Tominaga K, Kanamori A, Suzuki T, Kino H, Nakano M, Sugaya T, Tsuchida K, Majima Y, Murohisa T, Iijima M, Goda K, Irisawa A Abstract Objective: There is no consensus regarding administration of propofol for performing endoscopic submucosal dissection (ESD) in patients with comorbidities. The aim of this study was to evaluate the safety and efficacy of propofol-induced sedation administered by nonanesthesiologists during ESD of gastric cancer in patients with comorbidities classified according to the American Society of Anesthesiologists (ASA) physical status. Methods: Five hundred and twenty-two...
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
Gonadotropin and its role in the β-catenin/T-cell factor signaling pathway. Expert Rev Endocrinol Metab. 2007 May;2(3):375-385 Authors: Pon YL, Wong AS Abstract Gonadotropins, follicle-stimulating hormone and luteinizing hormone are key regulators in ovarian function, acting in an endocrine manner to regulate gametogenesis and steroidogenesis. In addition to normal tissue, gonadotropin receptors have also been demonstrated in ovarian carcinoma cell lines and primary tumors, suggesting that the gonadotropins may play a role in the pathophysiology of ovarian cancer. Thus, understanding mechanisms in...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Authors: Sasano H, Miki Y, Fukuda T, Nagasaki S, Nakata T, Suzuki T Abstract Aromatase inhibitors have become the gold standard of endocrine therapy in postmenopausal patients with estrogen receptor-positive or estrogen-dependent breast carcinoma, replacing tamoxifen. However, it is true that there are some potential problems to be overcome or improved on regarding aromatase inhibitor treatment of breast cancer. This especially includes the presence of the estrogen receptor-positive patients who do not necessarily respond to aromatase inhibitors, may require other modes of endocrine therapy and develop resistance t...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Role of TNF-α in human female reproduction. Expert Rev Endocrinol Metab. 2009 May;4(3):273-282 Authors: Calleja-Agius J, Muttukrishna S, Jauniaux E Abstract TNF-α is a highly versatile cytokine, playing an important role in both apoptosis and inflammation, which is central to reproduction. It belongs to the Th1 type of cytokines. Thus, TNF-α is a proinflammatory cytokine and is involved during follicle development and ovulation, corpus luteum formation and regression and cyclic endometrium function. It has been postulated to be detrimental to the survival of the conceptus due to apopt...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Authors: Ye J Abstract Dr Jianping Ye is a Professor at the Pennington Biomedical Research Center, Louisiana State University (LA, USA). He completed his graduate education in the medical school, Beijing University (China) in 1989 and moved to the USA to undertake postdoctoral research in 1992. He conducted research in the role of inflammation in cancer and was an instructor at the Health Science Center at San Antonio, University of Texas (TX, USA) in 1997, and assistant professor in the West Virginia University (WV, USA) in 1999. In 2001, he set up his lab at the Pennington Biomedical Research Center, Louisiana St...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Authors: Jones HE, Gee JM, Hutcheson IR, Nicholson RI Abstract Insulin-like growth factor-I receptor (IGF-IR) signaling is involved in many fundamental adverse aspects of cancer cell biology, such as proliferation, cell survival and migration. Its anti-apoptotic properties have implicated the receptor in mediating decreased sensitivity to chemotherapeutic drugs and radiation treatment; however, data are emerging that also indicates a role for IGF-IR signaling in resistance, not only to antihormones but also to antigrowth factor strategies such as agents that target the erb family of receptors. As such, IGF-IR is cl...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Authors: Ringe JD Abstract Zoledronic acid is a potent bisphosphonate widely used to counteract cancer-related bone loss. Once-yearly or even less frequent doses may be an effective therapy for benign bone disorders and may also result in improved compliance and tolerability. Data from two Phase III clinical trials have demonstrated the efficacy and safety of zoledronic acid in the treatment of Paget's disease of bone. Other studies have provided preliminary evidence for the utility of zoledronic acid in osteoporosis and other benign bone disorders. The major adverse effects associated with zoledronic acid infusion...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
More News: Brain | Brain Cancers | Cancer | Cancer & Oncology | Chemistry | Children | Eyes | Health | International Medicine & Public Health | Itchiness | Lyme Disease | Neurology | Nutrition | Oral Cancer | Pregnancy | Skin | Study | Tickborne Diseases | Toxicology | West Nile Virus | WHO | Women