FDA Clears Elagolix (Orilissa) for Endometriosis Pain FDA Clears Elagolix (Orilissa) for Endometriosis Pain

Elagolix is the first oral gonadotropin-releasing hormone antagonist specifically developed for the treatment of moderate to severe pain associated with endometriosis.FDA Approvals
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Family Medicine/Primary Care News Alert Source Type: news

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Publication date: Available online 16 November 2018Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Ticiana A.A. Mira, Paulo C. Giraldo, Daniela A. Yela, Cristina L. Benetti-Pinto
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Some people use a transcutaneous electrical nerve stimulation (TENS) unit to treat pain. This device works by sending electrical impulses through the skin. It may give people relief from the painful symptoms of arthritis, multiple sclerosis, fibromyalgia, endometriosis, and other conditions. Learn more here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news
To evaluate whether endometriosis is associated with depressive symptoms, and whether the association is modulated by pelvic pain.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Systematic Review Source Type: research
Authors: Zheng W, Cao L, Xu Z, Ma Y, Liang X Abstract Endometriosis is caused by the growth or infiltration of endometrial tissues outside of the endometrium and myometrium. Symptoms include pain and infertility. Surgery and hormonal therapy are widely used in Western medicine for the treatment of endometriosis; however, the side effects associated with this practice include disease recurrence and menopause, which can severely influence quality of life. Angiogenesis is the main biological mechanism underlying the development of endometriosis. Numerous natural products and Chinese medicines with potent anti-angiogen...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
A systematic review discusses the efficacy of this approach to controlling endometriosis-related pain.Medscape Ob/Gyn
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Viewpoint Source Type: news
BackgroundTo establish whether the ultrasound findings of minimal endometriosis are confirmed at laparoscopy and that a correlation can be established as to the anatomical sites in this mild form of the disease.AimsPatients with pain and suspicion of endometriosis had an ultrasound scan by a sonologist with expertise in endometriosis as part of their pre ‐operative workup.Measurements and Main resultsThe clinical histories of 53 patients who had laparoscopy to investigate pelvic pain were reviewed. Ultrasounds were performed between 2012 and 2015 by a single sonologist with expertise in endometriosis assessments. The ult...
Source: The Australian and New Zealand Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Tags: Original Article Source Type: research
Publication date: Available online 6 November 2018Source: Pharmacological ResearchAuthor(s): Fatemeh Bina, Samaneh Soleymani, Tayebeh Toliat, Mannan Hajimahmoodi, Malihe Tabarrai, Mohammad Abdollahi, Roja RahimiAbstractEndometriosis is an estrogen-dependent disease with inflammatory lesions at extra-uterine sites, causing pelvic pain and fertility reduction. Conventional therapies primarily focus on reducing systemic levels of estrogens; however, they do not have desirable effectiveness and possess considerable side effects. Therefore, there is a growing interest in the use of herbal medicine for the treatment of endometri...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 3 November 2018Source: Best Practice &Research Clinical Endocrinology &MetabolismAuthor(s): Dominique de Ziegler, Paul Pirtea, Marie Carbonnel, Marine Poulain, Ettore Cicinelli, Carlo Bulletti, Konstantinos Kostaras, George Kontopoulos, David Keefe, Jean Marc AyoubiAbstractEndometriosis – a disease causing pain and infertility – is encountered in nearly 50% of infertile women. While medical treatment is effective on pain and recurrence of symptoms after surgical excision, it is of no help for treating infertility for which the only options considered are surgery and AR...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research
ConclusionGiven the potential for endometrial appendicitis, we propose appendectomy in reproductive age female patients with right lower quadrant pain, regardless of appendix appearance on laparoscopy.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Endometriosis – a disease causing pain and infertility – is encountered in nearly 50% of infertile women. While medical treatment is effective on pain and recurrence of symptoms after surgical excision, it is of no help for treating infertility for which the only options considered are surgery and ART.Surgery enhances the chances of conceiving naturally during the 12-18 ensuing months irrespective of the stage of the disease. Surgery however is of no help when ART is considered, as it does not improve outcome and can only harm the ovarian response to stimulation.
Source: Best Practice and Research. Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Source Type: research
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