Resveratrol treatment reduces the appearance of tubular aggregates and improves the resistance to fatigue in aging mice skeletal muscles.

This study reports the effects of a 0,04% RES-supplemented diet for six months, on the skeletal muscle properties of C57/BL6 aging mice. The analysis of the morphology, protein expression, and functional-mechanical properties of selected skeletal muscles in treated compared to control mice, revealed that treated animals presented less tubular aggregates and a better resistance to fatigue in an ex-vivo contraction test, suggesting RES as a good candidate to reduce age-related alterations in muscle. PMID: 30036632 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30036632?dopt=Abstract

Source: Experimental Gerontology - July 20, 2018 Category: Geriatrics Authors: Toniolo L, Fusco P, Formoso L, Mazzi A, Canato M, Reggiani C, Giacomello E Tags: Exp Gerontol Source Type: research