Serine protease PRSS55 is crucial for male mouse fertility via affecting sperm migration and sperm-egg binding.

In conclusion, we have demonstrated that PRSS55 plays vital roles in regulating male fertility of mice, including in vivo sperm migration and in vitro sperm-egg interaction, possibly by affecting the maturation of ADAM3 in sperm and the expression of multiple genes in testis.
PMID: 30032357 [PubMed - as supplied by publisher]

Source: Cellular and Molecular Life Sciences : CMLS - July 21, 2018 Category: Cytology Authors: Shang X, Shen C, Liu J, Tang L, Zhang H, Wang Y, Wu W, Chi J, Zhuang H, Fei J, Wang Z Tags: Cell Mol Life Sci Source Type: research