Progression of electrocardiographic abnormalities associated with initial ventricular fibrillation in asymptomatic patients with Brugada syndrome

Various risk stratifications in asymptomatic patients with Brugada syndrome (BrS) have been proposed, but the electrophysiological change that promotes ventricular fibrillation (VF) is still unknown.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research

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Publication date: Available online 11 November 2019Source: Regulatory Toxicology and PharmacologyAuthor(s): Yonglin Gao, Guangfei Wang, Tong Wang, Guisheng Li, Jian Lin, Liqin Sun, Xuran Wu, Xilin Sun, Hongbo Wang, Chunmei Li, Jingwei Tian, Jing Zhu, Kezhou Wang, Susan ChoAbstract20(s)-ginsenoside Rg3 is a red ginseng-derived compound with the formula C42H72O13 that has been increasingly used by humans, leading to safety concerns regarding this use. In the current study, we conducted a 26-week study during which 20(S)-ginsenoside Rg3 (0, 7, 20, or 60 mg/kg) was continuously administered orally to Beagle dogs in order to ...
Source: Regulatory Toxicology and Pharmacology - Category: Toxicology Source Type: research
TUESDAY, Nov. 12, 2019 -- In two studies, artificial intelligence was used with electrocardiogram (ECG) results to identify patients who are at increased risk for a potentially dangerous irregular heartbeat, and those more likely to die within a...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Publication date: March 2020Source: Biomedical Signal Processing and Control, Volume 57Author(s): Mohammad Reza Mohebbian, Mohammad Wajih Alam, Khan A. Wahid, Anh DinhAbstractAn electrocardiogram (ECG) is used to record the electrical activity of the heart. However, ECG signals are susceptible to the noise from various sources which increases the probability of misinterpretation and can affect the diagnostic process. Traditional noise cancellation techniques, which uses finite and deterministic coefficient, are not efficient, since the ECG signals are non-stationary. Thus, adaptive filters are commonly utilized on such sig...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
A middle-aged, asymptomatic woman with a medical history of Bartter syndrome and chronic kidney disease presented to the ambulatory clinic for a routine outpatient colonoscopy. The nurse practitioner ordered a resting 12-lead electrocardiogram to screen for prolongation of the corrected QT (QTc) interval, associated with increased risk for arrhythmia. The patient was in normal sinus rhythm at 77 beats/min. The QTc was 426 milliseconds. Notched P waves and a negative P terminal force in lead V1 were present.
Source: The Journal for Nurse Practitioners - Category: Nursing Authors: Tags: Case Challenge Source Type: research
Electrocardiographic (ECG) methods to assess area at risk (AAR) and infarct size (IS) in patients with ST-elevation myocardial infarction (STEMI) have been previously established but not validated against contemporary benchmark Cardiac Magnetic Resonance (CMR) measures. We compared ECG-determined and CMR-determined measures for (a) AAR, (b) IS, and (c) myocardial salvage.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
We thank Sodhi and Hussain for their interest in our  work. We appreciate their acknowledgement of the benefit of education in electrocardiogram (ECG) interpretation to improve ECG reading skills and confidence in those who do not use ECGs extensively in their daily practices.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Letters to the editor Source Type: research
A 40-year-old man was treated with tonsillectomy and underwent early surgical exploration because of bleeding. Postoperative bleeding complications were treated with bronchoscopy. In addition to obesity, normal thyroid function, type 2 diabetes mellitus, and current tobacco abuse with severe obstructive sleep apnea syndrome, biochemistry revealed severe hypercholesterolemia (total cholesterol 572 mg/dL) and hypertriglyceridemia (1,220 mg/dL). During the postoperative period, low doses of propofol (up to 2 mg/kg/h for 10 hours), along with remifentanil (up to 0.0016 mg/kg/h for 20 hours), midazolam, and tramadol, were neede...
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Letter to the Editor Source Type: research
Study results published this week in the Journal of the American College of Cardiology: Clinical Electrophysiology show that an investigational set of algorithms in Medtronic's Micra transcatheter pacing system (TPS) significantly improves synchrony and cardiac function in patients with impaired electrical conduction between the chambers of the heart, a condition called atrioventricular (AV) block. The results from the MARVEL 2 study are expected to be presented Nov. 16 at the American Heart Association's annual scientific sessions. Medtronic said that based on positive results from both...
Source: MDDI - Category: Medical Devices Authors: Tags: Implants Source Type: news
To examine differences in image quality of the coronary arteries when performing high-pitch non-electrocardiography (ECG)-gated scans on the second-generation (2G) and third-generation (3G) dual-source CT scanners.
Source: Clinical Imaging - Category: Radiology Authors: Tags: Cardiothoracic Imaging Source Type: research
Publication date: March 2020Source: Biomedical Signal Processing and Control, Volume 57Author(s): Federico Guede-Fernández, Víctor Ferrer-Mileo, Marc Mateu-Mateus, Juan Ramos-Castro, Miguel Ángel García-González, Mireya Fernández-ChimenoAbstractA measurement method of heart rate and heart rate variability (HRV) based on smartphone has been developed and validated. The method is based on photoplethysmography (PPG) acquired with the smartphone camera (SPPG). SPPG was compared with the electrocardiogram (ECG), used as the gold standard, and with an external PPG sensor. Twenty-three he...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
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