Late-Onset Epilepsy Tied to APOE Status (CME/CE)

(MedPage Today) -- Modifiable vascular, lifestyle risk factors also play a role
Source: MedPage Today Primary Care - Category: Primary Care Source Type: news

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Authors: Carota A, Bogousslavsky J Abstract Hallucinations, delusions, and confabulations are common symptoms between neurology and psychiatry. The neurological diseases manifesting with such symptoms (dementia, epilepsy, Korsakoff's disease, brain tumors, Parkinson's disease, migraine, right hemisphere stroke and others) would be the key to understand their biological mechanisms, while the cognitive sciences, neuropharmacology and functional neuroimaging would be the tools of such researches. It is possible to understand the perceptive rules of the mind and the mechanisms of the human consciousness based on these ...
Source: Frontiers of Neurology and Neuroscience - Category: Neuroscience Tags: Front Neurol Neurosci Source Type: research
Publication date: August 2019Source: Epilepsy &Behavior, Volume 97Author(s): Siqi Ding, Xueying Li, Yingjie Hua, Feirong Dong, Jiahe Lin, Yanru Du, Jingzan Shen, Niange Xia, Zhenguo Zhu, Xinshi Wang, Rongyuan Zheng, Huiqin XuAbstractObjectiveThe major cause of premature mortality in people with epilepsy (PWE) is suicide. Actual data on the risk of suicidal tendency in adult PWE in China are scarce. In our study, associations between possible risk factors and suicidal tendency in adult PWE in China were investigated.MethodsPeople with epilepsy (n = 251) were recruited, and their demographic and clinical characterist...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
This article is part of the Special Issue “Seizures &Stroke”.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Source: Seizure: European Journal of Epilepsy - Category: Neurology Source Type: research
Publication date: September 2019Source: Biomedicine &Pharmacotherapy, Volume 117Author(s): Gamal A. Salem, Fathi B. Alamyel, Faraj A. Abushaala, khloud A. Elnory, Hawa Abusheba, Ravi P. SahuAbstractChrysanthemum trifurcatum is common to Mediterranean countries and widely-used in traditional medicine. Due to the scarcity of data about the pharmacological properties of C. trifurcatum, this present study was designed to determine the effects of C. trifurcatumethanolic extract (CEE) for its anti-nociceptive, anti-epileptic, anti-inflammatory, and hepatoprotective activities in mice and rat models. We demonstrate that CEE c...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 22 June 2019Source: Seminars in Cell &Developmental BiologyAuthor(s): Maude Bordeleau, Micaël Carrier, Giamal N. Luheshi, Marie-Ève TremblayAbstractIn addition to their traditional role as immune sentinels, recent discoveries over the last decade have shown that microglial functions now include regulation of neuronal/glial cell migration, differentiation and maturation, as well as neuronal network formation. It was thus proposed that disruption of these microglial roles, during critical periods of brain development, could lead to the pathological onset of several neurodeve...
Source: Seminars in Cell and Developmental Biology - Category: Cytology Source Type: research
ConclusionsWe conclude, that in particular posterior shoulder dislocations are often caused by a first seizure and should always raise the suspicion of an epileptic seizure even in the absence of a clear history. AED treatment likely has a protective effect against this type of injury, even if seizure-freedom is not achieved.
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 20 June 2019Source: SeizureAuthor(s): Randi von Wrede, Susanna Moskau-Hartmann, Theodor Ruber, Christoph Helmstaedter, Rainer Surges
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 20 June 2019Source: Pharmacological ResearchAuthor(s): Santiago J. Ballaz, George V. RebecABSTRACTAscorbic acid (AA) is a water-soluble vitamin (C) found in all bodily organs. Most mammals synthesize it, humans are required to eat it, but all mammals need it for healthy functioning. AA reaches its highest concentration in the brain where both neurons and glia rely on tightly regulated uptake from blood via the glucose transport system and sodium-coupled active transport to accumulate and maintain AA at millimolar levels. As a prototype antioxidant, AA is not only neuroprotective, but also...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Juvenile myoclonic epilepsy (JME) is characterized by the presence of bilateral myoclonic, generalized myoclonic, tonic –clonic, and (less often) absence seizures. Its prevalence comprises 5–10% of all epilepsies and 18% of genetic (idiopathic) generalized epilepsies [1]. Clinical symptoms occur between 6 and 22 years of age, most frequently during adolescence: age at onset is 13–16 years in half of affected pa tients [2]. Myoclonic seizures primarily occur between 12 and 18 years of age; these consist of generalized tonic–clonic (GTC) seizures in 80–97% of patients [3].
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research
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