LAZ3 protects cardiac remodeling in diabetic cardiomyopathy via regulating miR-21/PPARa signaling.

In conclusion, LAZ3 protects against cardiac remodeling in DCM by decreasing miR-21, thus regulating PPARa/NRF2 signaling.
PMID: 30031228 [PubMed - as supplied by publisher]

Source: Biochimica et Biophysica Acta - July 18, 2018 Category: Biochemistry Authors: Gao L, Liu Y, Guo S, Xiao L, Wu L, Wang Z, Liang C, Yao R, Zhang Y Tags: Biochim Biophys Acta Source Type: research