Propofol, Breast Cancer Cells, the Immune System, and Outcome Propofol, Breast Cancer Cells, the Immune System, and Outcome

This study reviews the effects of propofol on breast cancer cell biology, the immune system, and post-op pain.BMC Anesthesiology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

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CONCLUSION In the majority of patients, pain after breast cancer surgery decreased rapidly and disappeared or the intensity decreased over 3 years. However, in about a tenth of patients, moderate-to-severe pain tended to increase during the 3-year follow-up.
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Pain Source Type: research
A case of secretory breast cancer in a 6 year-old girl: is it possible to make a correct preoperative diagnosis? Breast Cancer. 2020 Jan 30;: Authors: Gohara T, Komura M, Asano A, Emura T, Obana K, Kikuchi T, Yonekawa H, Komuro H, Kodaka T, Terawaki K, Saeki T, Osaki A, Li CP, Ishizawa K, Hasebe T, Tsuda H, Sasaki A Abstract Secretory breast carcinoma constitutes the majority of breast cancers in children and young people less than 20 years of age. Noninvasive examination is particularly necessary for the diagnosis of breast carcinoma in children. Herein, we report a case of secretory breast...
Source: Breast Cancer - Category: Cancer & Oncology Authors: Tags: Breast Cancer Source Type: research
Conclusion: Both blocks result in equally prolonged analgesia and preclude requirement of opioid analgesics intra and post-operatively. PECS block is associated with lesser time to allow incision. Complications are low in both the groups. Routine use of these blocks to avoid opioids may be studied further. Clinical trial number – Registered in Clinical Trials Registry of India (CTRI/2017/02/007897). http://ctri.nic.in.
Source: Journal of Anaesthesiology Clinical Pharmacology - Category: Anesthesiology Authors: Source Type: research
D Krishna Sumanth, Abhijit S Nair, Srinivasa S P Mantha, Basanth K RayaniIndian Journal of Anaesthesia 2019 63(12):1036-1038
Source: Indian Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research
ConclusionsPecs2 blocks can significantly reduce post-operative pain, nausea and vomiting in patients undergoing mastectomy. Their use can enable units to achieve high day-case mastectomy rates.
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research
Conditions:   Anesthesia;   Analgesia;   Acute Pain;   Chronic Pain;   Pectoralis Nerve Block;   Erector Spine Plane Block;   Patient Controlled Analgesia Interventions:   Procedure: Pectoralis nerve block;   Procedure: Erector spine plane block;   Other: Control Sponsors:   Ondokuz Mayıs University;   CENGİZ KAYA (ckaya) Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 20 October 2019Source: The LancetAuthor(s): Daniel I Sessler, Lijian Pei, Yuguang Huang, Edith Fleischmann, Peter Marhofer, Andrea Kurz, Douglas B Mayers, Tanja A Meyer-Treschan, Martin Grady, Ern Yu Tan, Sabry Ayad, Edward J Mascha, Donal J Buggy, Gang Tan, Zhiyong Zhang, Helen Keane, Maurice Stokes, Oliver Zotti, Michael Gnant, Silvia Perez-ProttoSummaryBackgroundThree perioperative factors impair host defence against recurrence during cancer surgery: the surgical stress response, use of volatile anaesthetic, and opioids for analgesia. All factors are ameliorated by regional anaesthesia...
Source: The Lancet - Category: General Medicine Source Type: research
This study tested the hypothesis that vascular endothelial growth factor A and vascular endothelial growth factor receptor 2 contribute to bone cancer pain regulation associated with spinal central sensitization.Methods This study was performed on female rats using a metastatic breast cancer bone pain model. Nociceptive behaviors were evaluated by mechanical allodynia, thermal hyperalgesia, spontaneous pain, and CatWalk gait analysis. Expression levels were measured by real-time quantitative polymerase chain reaction, western blot, and immunofluorescence analysis. Excitatory synaptic transmission was detected by whole-cell...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Authors: Cassai A, Bonanno C, Sandei L, Finozzi F, Carron M, Marchet A Abstract Background: Breast cancer is complicated by a high incidence of chronic postoperative pain (25%-60%). Regional anesthesia might play an important role in lowering the incidence of chronic pain; however it is not known if the pectoral nerve block (PECS block), which is commonly used for breast surgery, is able to prevent this complication. Our main objective was therefore to detect any association between the PECS block and chronic pain at 3, 6, 9, and 12 months in patients undergoing breast surgery. Methods: We conducted a prospecti...
Source: Korean Journal of Pain - Category: Anesthesiology Tags: Korean J Pain Source Type: research
AbstractPurposeThe aim of the present study was to determine the levels of anxiety of partners of breast cancer patients and to evaluate the differences of anxiety levels between patients and partners according to the stage of treatment, age and education level.Methods57 spouses or domestic partners of breast cancer patients and 148 breast cancer patients participated in this prospective cohort study and filled out the questionnaires including the Spielberger state-trait-anxiety-inventory, as well as questions based on stress-triggering procedures during breast cancer diagnosis and therapy.ResultsState anxiety levels of pa...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
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