Behavioral Tagging: Plausible involvement of PKMζ, Arc and role of neurotransmitter receptor systems
Publication date: Available online 20 July 2018Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Shruti Vishnoi, Mehar Naseem, Sheikh Raisuddin, Suhel ParvezAbstractThere are many evidences in support of Behavioral Tagging hypothesis that relies on the setting of a learning tag and the synthesis of plasticity related proteins (PRPs). It explains that how a learning tag produced as a result of weak training can be paired up with PRPs that arrive as a result of novelty and consequently lead to long lasting memories. In the following review we have focused on possible involvement of PKMζ, Arc as PRPs and neurotransmitter receptor systems ACh, metabotropic glutamate in behavioral tagging along with evidences in support of involvement of dopamine, NMDA glutamate and β-adrenergic receptor systems in behavioral tagging.
Authors: Zhylkaidarova A, Kaidarova D, Batyrbekov K, Shatkovskaya O, Begimbetova D Abstract We carried out an analysis of the total incidence of colon cancer throughout Kazakhstan. Retrospectively, according to the regional reports on endoscopic screening, the study showed an increase in the age-related incidence of colorectal cancer (CRC) cases from 2004-2008 to 2009-2014. The peak of morbidity in both periods was noted in the age category of>70 years. The indicators of the territorial distribution of CRC incidence make it possible to divide the regions into areas with low or high rates of CRC. Specific indicat...
Conclusions: The transduodenal approach for obtaining samples from solid lesions using a 19-G flexible needle seems feasible and accurate. PMID: 32447874 [PubMed - as supplied by publisher]