Intensive versus Moderate Statin Therapy and Early Graft Occlusion after Coronary Bypass Surgery: The ACTIVE Randomized Clinical Trial

Statins prevent saphenous vein graft (SVG) disease and improve outcomes after coronary artery bypass graft surgery (CABG). However, the optimal postoperative statin dose remains unclear. The Aggressive Cholesterol Therapy to Inhibit Vein Graft Events (ACTIVE) trial was undertaken to evaluate whether early postoperative high-dose statin therapy reduces SVG occlusion compared to conventional moderate-dose therapy.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research