Inactivation of Sirtuin2 protects mice from acetaminophen-induced liver injury: possible involvement of ER stress and S6K1 activation.

This study elucidates the molecular mechanisms underlying the protective role of Sirt2 inactivation in APAP-induced liver injuries.
PMID: 30021675 [PubMed - as supplied by publisher]

Source: BMB Reports - July 19, 2018 Category: Biochemistry Authors: Lee DH, Lee B, Park JS, Lee YS, Kim JH, Cho Y, Jo Y, Kim HS, Lee YH, Nam KT, Bae SH Tags: BMB Rep Source Type: research