A case of unusual histiocytic colitis in a chronic alcoholic obese patient with ankylosing spondylitis.

A case of unusual histiocytic colitis in a chronic alcoholic obese patient with ankylosing spondylitis. Acta Gastroenterol Belg. 2018 Apr-Jun;81(2):327-329 Authors: Guerra Diaz N, Sempoux C, Jouret-Mourin A, de Burbure C, Druez P Abstract A 64 year-old Caucasian man was first investigated 21 years ago for persistent diarrhoea. A colonoscopy revealed an erosive pancolitis with unusual vacuolated macrophages. Characteristics of ulcerative colitis or Crohn's disease were absent. Similar findings were observed consistently over the following years. A treatment with Sulfasalazine, Methotrexate or Budesonide was efficient. Histiocytic colitis is rare, and the various causes and different diagnoses are reviewed. The cause for the chronic pancolitis in this obese chronic alcoholic remains unknown at the time of writing. Links to the dyslipidaemia and chronic ankylosing spondylitis presented by the patient are possible hypotheses worth investigating further. PMID: 30024706 [PubMed - in process]
Source: Acta Gastro-Enterologica Belgica - Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research