Utility of liver biopsy in the evaluation of pediatric total parenteral nutrition cholestasis

ConclusionsLiver biopsy in patients with TPN cholestasis was associated with an increase in utilization of ursodeoxycholic acid. The effects of this are not fully understood; however, liver biopsy was not associated with improved patient outcomes such as LOS or mortality.SummaryThe utilization of liver biopsy in the evaluation of TPN cholestasis in neonates is unknown. The only change in management after liver biopsy was an increase in the use of ursodeoxycholic acid; however, did not lead to changes in patient outcomes.
Source: The American Journal of Surgery - Category: Surgery Source Type: research