In-hospital infective endocarditis following transcatheter aortic valve replacement: a cross-sectional study of the National Inpatient Sample database in the USA
Publication date: Available online 25 May 2018Source: Journal of Hospital InfectionAuthor(s): I. Yeo, L.K. Kim, S.O. Park, S.C. WongSummaryBackgroundWhile the utilization of transcatheter aortic valve replacement (TAVR) for patients with severe aortic stenosis has been increasing, in-hospital infective endocarditis (IE) following TAVR has not been well described.AimTo identify in-hospital IE following TAVR.MethodsAll patients who underwent TAVR between 2012 and 2014 were identified using the National Inpatient Sample database. Multi-variate logistic regression was performed to identify the predictors of in-hospital IE after TAVR.FindingsOf the 41,025 patients who received TAVR, 120 patients (0.3%) developed in-hospital IE. Viridans group streptococci (20.8%) was the most frequent causative organism for in-hospital IE, followed by Staphylococcus aureus (16.7%) and enterococci (8.3%). Patients who developed in-hospital IE after TAVR had significantly higher rates of death (20.8% vs 4.1%, P
CONCLUSIONS: The average patient is middle aged (often male) with a history of subacute back pain, sometimes presenting fever and/or neurological damage on diagnosis. Acute phase reactants are frequently raised. Diabetes mellitus, endocarditis and immunosuppressed patients may have the worst chance of a good outcome, therefore these patients should be more carefully managed (always try to obtain an imaging-guided biopsy, correct antibiotic treatment, and a functional and clinical follow-up). PMID: 32446680 [PubMed - as supplied by publisher]
This study, for instance, attributes a patient’s waitlist/transplant outcome to the very last dialysis facility the patient was associated with. In epidemiology speak, this means the causal inference authors are trying to draw between for-profit status and good transplant outcomes is subject to time-varying confounding. As an example, if one is seeking an association between testosterone levels and risk of a heart attack, using the last testosterone level available would be a poor way of doing this study because testosterone levels are known to vary over time. The same applies to dialysis facilities. Patie...
Publication date: August 2020Source: Biomedicine &Pharmacotherapy, Volume 128Author(s): Mohammad Reza Farahpour, Ehsan Pirkhezr, Ali Ashrafian, Ali Sonboli
BRIAN MAY has revealed today he recently suffered a heart attack at home and was "very near death" without realising. What were the Queen guitarist's symptoms?
CONCLUSION: As an easily accessible parameter, WBV might be a useful predictor of LVT formation within one year following acute anterior myocardial infarction. PMID: 32444531 [PubMed - as supplied by publisher]
Conditions: Chronic Renal Failure; Renal Insufficiency, Chronic Intervention: Sponsor: Clinique Néphrologique Saint-Exupéry Not yet recruiting
Condition: Stenosis of Arteriovenous Dialysis Fistula Interventions: Device: temporary hemodialysis catheters; Device: long-term hemodialysis catheters Sponsor: Shanghai Pudong Hospital Not yet recruiting
Condition: Mitral Regurgitation Functional Intervention: Device: MitraClip implantation Sponsor: IRCCS San Raffaele Recruiting
Condition: End Stage Renal Disease Interventions: Diagnostic Test: Venography; Diagnostic Test: Intravascular ultrasound (IVUS); Other: Image processing Sponsor: Boston Medical Center Not yet recruiting
Publication date: Available online 25 May 2018Source: Journal of Hospital InfectionAuthor(s): Ilhwan Yeo, Luke K. Kim, Sun O. Park, S. Chiu WongSummaryBackgroundWhile the utilization of transcatheter aortic valve replacement (TAVR) for patients with severe aortic stenosis has been increasing, in-hospital infective endocarditis (IE) following TAVR has not been well-described.AimTo identify in-hospital IE following TAVR.MethodsUsing the National Inpatient Sample database, we identified all patients who underwent TAVR between 2012 and 2014. Multivariate logistic regression was performed to identify the predictors of in-hospit...
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