Comprehensive substrate characterization of 22 antituberculosis drugs for multiple solute carrier (SLC) uptake transporters, in vitro.

In conclusion, this is the first study that, demonstrated 22 antituberculosis drugs interactions with transporters. This study will be helpful for mechanistic understanding of the disposition, drug-drug interactions and pharmacokinetics of these antituberculosis drugs. PMID: 30012768 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30012768?dopt=Abstract

Source: Antimicrobial Agents and Chemotherapy - July 16, 2018 Category: Microbiology Authors: Parvez MM, Kaisar N, Shin HJ, Lee YJ, Shin JG Tags: Antimicrob Agents Chemother Source Type: research