Management and treatment of deep vein thrombosis in special populations.

Management and treatment of deep vein thrombosis in special populations. Expert Rev Hematol. 2018 Jul 17;: Authors: Boon G, van Dam LF, Klok FA, Huisman MV Abstract INTRODUCTION: Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is the third most frequent cardiovascular disease besides myocardial infarction and stroke. Since DVT may cause life-threatening conditions, treatment should be started as soon as possible. This comprises certain challenges in special populations. Areas covered: In cancer-associated VTE, current treatment is different from non-cancer VTE due to disease-related interventions and higher bleeding risks. In treatment of patients with extensive DVT, the role of catheter-directed thrombolysis has been investigated in two randomised trials but results do not yield a recommendation for standard thrombolysis. The diagnosis of suspected recurrent DVT is especially challenging in case of ipsilateral DVT. Treatment strategies in recurrent DVT are dependent on the case and on particular risk factors. Also discussed is the therapy for DVT in pregnant women, which is more complex as a result of anticoagulants crossing the placenta. Expert commentary: DVT treatment in those special populations poses special challenges due to high thrombotic and bleeding risk. This will be discussed in more detail in this review. PMID: 30016119 [PubMed - as supplied by publisher]
Source: Expert Review of Hematology - Category: Hematology Tags: Expert Rev Hematol Source Type: research