Raised risk of MI and mortality when starting sulfonylurea

Continuing metformin when introducing sulfonylureas in type 2 diabetes safer than switching Related items fromOnMedica Sugar not saturated fat is the major issue for CVD Experts query risks of pioglitazone Regulators suspend Avandia over safety concerns Daily aspirin use linked to major bleeding Use of DPP-4 inhibitors associated with increased risk of IBD
Source: OnMedica Latest News - Category: UK Health Source Type: news

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AbstractStrongyloides stercoralis (S. stercoralis), a human intestinal nematode, can lead to hyper/disseminated (HD) infection in patients treated with corticosteroids. Here, we report a case of strongyloidiasis in a 58-year-old female with a history of rheumatoid arthritis (RA) and type 2 diabetes mellitus (T2DM). The patient presented with abdominal pain and gastrointestinal (GI) bleeding. Stool was negative for parasitic agents in the first direct smear examination, and the patient with the probable diagnosis ofHelicobacter pylori (H. pylori) infection or Crohn ’s disease received antibiotics and corticosteroids. ...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
This study investigated the local effect of photobiomodulation (PBM) for the treatment of periodontal pockets in patients with periodontitis and type 2 diabetes. Thirty-eight periodontal pockets presenting probing depth (PD) and clinical attachment level (CAL)  ≥ 5 mm were selected from 19 patients (two pockets/patient). The selected periodontal pockets were randomly assigned to receive mechanical debridement only (control group) or mechanical debridement with PBM (PBM group). Clinical measures, such as PD, CAL, bleeding on probing (BoP), and prese nce of supragingival biofilm (PI), were collected and...
Source: Lasers in Medical Science - Category: Laser Surgery Source Type: research
Cerebral stroke is a leading cause of death and persistent disability of elderly in the world. Moreover, after the age of 55, the risk of stroke doubles with each passing decade. Of all strokes, approximately 85 percent are ischemic, caused by blockage of cerebral arteries and remaining hemorrhagic, caused by intracerebral or subarachnoid bleeding. Although stroke prevention by targeting several risk factors such as diabetes, smoking, sedentary lifestyle, hypertension, alcohol abuse and hyperlipidemia have decreased the stroke incidence, the total number of strokes is increasing due to the population aging. After an ischem...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion In patients with T2DM, those with periodontitis may be more susceptible to decreased kidney function. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Experimental and Clinical Endocrinology and Diabetes - Category: Endocrinology Authors: Tags: Article Source Type: research
ConclusionsIn these patients with T2DM, cangrelor was comparable to clopidogrel in terms of efficacy at 48  h following PCI. However, it was associated with significantly higher mild GUSTO bleeding and major and minor ACUITY bleeding, therefore requiring further workups on its safety side. This hypothesis should be explored further and confirmed in other forthcoming trials based strictly on patients wit h T2DM.
Source: Diabetes Therapy - Category: Endocrinology Source Type: research
Experts have issued a new set of guidelines on the best ways to prevent first heart attacks, strokes and heart failure — and for the first time, they focus squarely on the patient. The new guidelines recognize how doctors can support people to not only address their medical risk factors, but also to change their behaviors and lifestyles in order to reduce their risk. The latest revisions to the guidelines, issued by the American College of Cardiology (ACC) and the American Heart Association (AHA), were announced at the annual meeting of the ACC. They are intended to help doctors figure out a patient’s risk of h...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Heart Disease Source Type: news
(CNN) — If you’re a healthy older adult looking for ways to reduce your risk of heart attack and stroke, don’t turn to that age-old standby: daily low-dose aspirin. It’s no longer recommended as a preventative for older adults who don’t have a high risk or existing heart disease, according to guidelines announced Sunday by the American College of Cardiology and the American Heart Association. “For the most part, we are now much better at treating risk factors such as hypertension, diabetes and especially high cholesterol,” said North Carolina cardiologist Dr. Kevin Campbell, who wa...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News aspirin CNN Source Type: news
Although the new oral P2Y12 inhibitors, prasugrel/ticagrelor have shown greater efficacy than clopidogrel in patients with the acute coronary syndrome, but they have not shown better efficacy in Korean patients. So we evaluated the efficacy of the prasugrel/ticagrelor in patients with myocardial infarction (MI) and diabetes, a more high-risk patients group. From the Korea Acute Myocardial Infarction Registry-National Institute of Health, 3985 patients with MI and diabetes who underwent PCI were enrolled between November 2011 and December 2015. The patients were divided into 2 groups: clopidogrel (nā€Š=ā€Š2985) and prasugr...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
CONCLUSION: most of type-2 diabetics had severe periodontitis; however, the correlation between periodontitis and arterial stiffness could not be concluded in this study. PMID: 30630997 [PubMed - in process]
Source: Acta medica Indonesiana - Category: Internal Medicine Tags: Acta Med Indones Source Type: research
AbstractDiabetes and periodontitis may increase risk of cardiovascular disease. Whether albuminuria, C-reactive protein (CRP), and socioeconomic factors, known as cardiovascular risks in subjects with poorly controlled diabetes, are independently associated with periodontal status in well-controlled diabetes remains to be elucidated. In 503 subjects with type 2 diabetes, the cross-sectional associations of clinical and socioeconomic factors with periodontal parameters were investigated. Periodontal parameters on all teeth included the probing pocket depth at 6 sites per tooth, bleeding on probing, the plaque score, tooth m...
Source: Diabetology International - Category: Endocrinology Source Type: research
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