Enhancing social functioning in young people at Ultra High Risk (UHR) for psychosis: A pilot study of a novel strengths and mindfulness-based online social therapy

Psychological and pharmacological treatments have been shown to reduce rates of transition to psychosis in Ultra High Risk (UHR) young people. However, social functioning deficits have been unresponsive to current treatments.
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research

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Tushar Kanti Das, Avyarthana Dey, Priyadharshini Sabesan, Alborz Javadzadeh, Jean Th éberge, Joaquim Radua, Lena Palaniyappan
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
DiscussionWe confirm that decreased peripheral neurotrophin levels are significantly associated with schizophrenia, thereby confirming the neurobiological hypothesis of neurotrophins in schizophrenia. Low levels of neurotrophins in peripheral blood of patients with schizophrenia may explain, in part, the pathophysiology of schizophrenia.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
 Most of us spend a large portion of our days at work, where we’re exposed to all sorts of different stressors that take a cumulative toll. And many of us are already dealing with some sort of mental health issue unrelated to our jobs. Put together, it can be a recipe for a breakdown, which is why it’s so important to address mental health in the workplace. Host Gabe Howard shares his insights on the subject, including his story of being fired from a job due to his mental illness, and the ensuing years of exploring the nature of mental health at our places of employment. Subscribe to Our Show! An...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Industrial and Workplace Mental Health and Wellness The Psych Central Show Gabe Howard Vincent M. Wales Source Type: blogs
Elderly patients with schizophrenia are a particularly vulnerable group often excluded from clinical trials. Currently there is no evidence-synthesis about the efficacy and safety of antipsychotics in this subgroup.We reviewed all randomized-controlled-trials, about antipsychotics in elderly schizophrenics (last search Dec 12, 2017). Pairwise meta-analyses were conducted. The primary outcome was overall symptoms. Secondary outcomes included positive symptoms, negative symptoms, response, dropouts, quality of life, social functioning and side-effects.
Source: European Neuropsychopharmacology - Category: Psychiatry & Psychology Authors: Source Type: research
Discussion An alarmingly high number of patients were at high risk of nonresponse to antipsychotic treatment. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Pharmacopsychiatry - Category: Psychiatry Authors: Tags: Original Paper Source Type: research
(MedPage Today) -- News and commentary from the psychiatry world
Source: MedPage Today Neurology - Category: Neurology Source Type: news
Publication date: Available online 18 September 2018Source: Neuroscience LettersAuthor(s): Yafei Kang, Kexin Huang, Suping Cai, Haidong Wang, Jixin Liu, Yubo Wang, Yahui Lv, Wei Zhang, Qiang Wang, Liyu Huang, Jijun Wang, Jie TianAbstractThe aberrant orchestration between the triple networks has been suggested as a backbone for some cognitive and clinical features of schizophrenia. The salience network (SN) plays a general role in switching between the central executive network (CEN) and the default mode network (DMN) mediated by dopamine activity. Whether the disease state and dopamine associated gene, catechol-O-methyltra...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Publication date: Available online 18 September 2018Source: Pharmacology Biochemistry and BehaviorAuthor(s): Peter U. Hámor, Jana Šírová, Tomáš Páleníček, Magdalena Zaniewska, Věra Bubeníková-Valešová, Marek SchwendtAbstractChronic methamphetamine (meth) abuse often turns into a compulsive drug-taking disorder accompanied by persistent cognitive deficits and re-occurring psychosis. Possible common neurobiological substrates underlying meth-induced deficits and schizophrenia remain poorly understood. Serotonin 2A (5-HT2A) and metabotropic ...
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
Authors: Laere E, Tee SF, Tang PY Abstract OBJECTIVE: The present meta-analysis aimed to analyze the cognitive performance of schizophrenia patients measured by Trail Making Tests (TMT) and the contribution of socio-demographic factors to cognitive impairments. METHODS: PubMed and PsycARTICLES databases were searched for the studies published between January 1985 and November 2017. Data were drawn from 19 studies encompassing 1095 patients and 324 controls. The effect size and heterogeneity were assessed with Comprehensive Meta-Analysis version 2 using random-effect model. RESULTS: Overall, the results show...
Source: Psychiatry Investigation - Category: Psychiatry Tags: Psychiatry Investig Source Type: research
Saeed Ahmed, Sanya Virani, Vijaya P. Kotapati, Ramya Bachu, Mahwish Adnan, Ali M. Khan, Aarij Zubair, Gulshan Begum, Jeevan Kumar, Mustafa Qureshi, Rizwan Ahmed
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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