Enhancing social functioning in young people at Ultra High Risk (UHR) for psychosis: A pilot study of a novel strengths and mindfulness-based online social therapy
Psychological and pharmacological treatments have been shown to reduce rates of transition to psychosis in Ultra High Risk (UHR) young people. However, social functioning deficits have been unresponsive to current treatments.
Caroline Madeira, Flavio V. Alheira, Marilia A. Calcia, Thuany C. S. Silva, Filippe M. Tannos, Charles Vargas-Lopes, Melissa Fisher, Nelson Goldenstein, Marco Antonio Brasil, Sophia Vinogradov, Sergio T. Ferreira, Rogerio Panizzutti
Conclusions Small changes in prolactin levels, low proportions of patients with postbaseline elevated prolactin values, and low incidence of prolactin-related TEAEs were observed after treatment with brexpiprazole.
Conclusions This study demonstrated that long-acting paliperidone palmitate therapy was associated with more favorable results in terms of medication adherence, drug side effects, and quality of life compared with second-generation oral antipsychotics. However, there is a need for further, more specific, and larger-scale studies in this field.
This article reviews the effects of cannabis in people with mental ill ness. Then, we provide a reconciliation of the addiction vulnerability and allostatic hypotheses to explain co-morbidity addiction in mentally ill cannabis users, as well as to further aid in developing a rational framework for the assessment and treatment of problematic cannabis use in these patien ts.
Conclusions: Core fucosylation negatively regulates the states of neuroinflammation by modulating the sensitivity of microglia and astrocytes to inflammatory mediators. The disorders of Fut8−/− mice are caused not only by neurons but also by glial cell dysfunction.General significance: Core fucose is a novel regulator for neuroinflammation in the central nervous system.
(Natural News) A high-tech computer game is being tested to find out if it holds potential as a remedy for people experiencing hallucinations, especially among schizophrenic patients. Should these intriguing conclusions be medically verified, it could introduce a new fun alternative to conventional psychiatric therapies. Scores of research have already suggested that while current treatment plans for...
This study aimed to investigate the relationship between serum profiles of prolactin and thyroid stimulating hormone (TSH) and sexual dysfunction in patients with schizophrenia treated with conventional antipsychotic medication. MATERIAL AND METHODS A hospital-based cross-sectional study included 118 patients, age range 18-57 years (55 men, 63 women), with a confirmed diagnosis of schizophrenia. All patients were stable after antipsychotic treatment. Serum levels of hormones, including prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), progesterone, testosterone, thyroid-stimulating ho...
Amanda L. Baker, Debbie Robson, Sharon Lawn, Marc L. Steinberg, Sandra Bucci, Ann McNeill, David J. Castle, Billie Bonevski
Publication date: Available online 17 December 2018Source: Journal of Psychiatric ResearchAuthor(s): Cecilie Bay-Richter, Henriette Nørmølle Buttenschøn, Ole Mors, Amanda Eskelund, David Budac, Linda Kærlev, Gregers WegenerAbstractToxoplasma gondii (TOX) is a common parasite which infects approximately one third of the human population. In recent years, it has been suggested that latent toxoplasmosis may be a risk factor for the development of mental disorders, particularly schizophrenia and anxiety. With regards to depression the results have been varied.The main objective of this study was to e...
Conclusion. Spinal injuries in suicidal jumpers differed from spinal injuries in non-suicidal patients with regard to sex, age, mental health condition, injury location, neurologic damage, and associated injuries. Most survivors of suicidal jumping were young female patients with mental health problems. They tended to have thoracic and lumbar spine trauma rather than cervical trauma with less severe neurological deficits and a higher incidence of accompanying limb injury. Level of Evidence: 3