Falls and Fall-Related Injuries Among Older Adults With CKD Falls and Fall-Related Injuries Among Older Adults With CKD

This study investigated whether older adults with chronic kidney disease are at increased risk of falling and serious injury from falls. What factors might contribute to higher risk?Preventing Chronic Disease
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

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mEpoR-/- hEpoR+: The mouse Erythropoietin Receptor knockout that contains a human Erythropoietin Receptor transgene can be used to define the potency of recombinant erythropoietin preparations used to treat anemia associated with chronic kidney disease.Erythropoietin, acting by binding to Erythropoietin receptors (EpoR) on erythroid progenitor cells, is required for erythropoiesis. Absence of erythropoietin or the EpoR in mice interrupts erythropoiesis in the fetal liver and result in death at embryonic day 13.5. An 80-kb human EpoR transgene bred onto a mouse EpoR null background (provided by F. Constantini of Columbia Un...
Source: NIDDK Research Resources - Category: Endocrinology Source Type: research
Screening athletes, AF ablation complications, physician gender and MI mortality, the rise of chronic kidney disease, and the rosuvastatin lawsuit are discussed in this week's podcast.theheart.org on Medscape
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Cardiology Commentary Source Type: news
Authors: Kim KS, Park SW, Cho YW, Kim SK Abstract BACKGROUND: To evaluate the prevalence of chronic kidney disease (CKD) and progression rate to CKD in elderly patients with type 2 diabetes mellitus (T2DM). METHODS: We investigated the medical records of 190 elderly patients (65 years or older) with T2DM from 2005 to 2011 in 6-month increments. Mean follow-up duration was 64.5 months. CKD was defined as estimated glomerular filtration rate (eGFR)
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
Conclusion: In this single-center study with moderate sample size, the data showed no relationship of PCSK9 levels with normal or decreased eGFR in untreated patients with normal SCr, suggesting that further studies may be needed to understand the relationship between PCSK9 and lipid disorder in different stage of kidney dysfunction.Cardiorenal Med 2018;8:311 –320
Source: Cardiorenal Medicine - Category: Urology & Nephrology Source Type: research
FRIDAY, Aug. 17, 2018 -- Pediatric patients with chronic kidney disease (CKD) have higher global cerebral blood flow (CBF) and regional differences in CBF, according to a study published recently in Radiology. Hua-Shan Liu, Ph.D., from Taipei...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
CONCLUSIONS: In the EXCEL trial, PCI of LM disease with TRA was associated with comparable early and late clinical outcomes as TFA. PMID: 30111521 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Heatwaves have ravaged much of the northern hemisphere, causing wildfires, destruction and death. Some are blaming heat stress for an increase in chronic kidney disease in Central America.Graihagh Jackson investigates the causes and health effects of heatwavesSubscribe and review onAcast,Apple Podcasts,Soundcloud,Audioboom andMixcloud. Join the discussion onFacebook andTwitterHeatwaves have hit many parts of the northern hemisphere this summer, ravaging landscapes and causing death and destruction in their wake. Wildfires have broken out in the Arctic Circle, as well as inCalifornia,Sweden andGreece. People are dying from ...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Science Climate change Environment Weather Wildfires Source Type: news
Publication date: Available online 16 August 2018Source: Canadian Journal of CardiologyAuthor(s): Bryan J. Har, Matthew T. James
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Seguro Vitamin D (VD) is a pro-hormone essential for life in higher animals. It is present in few types of foods and is produced endogenously in the skin by a photochemical reaction. The final step of VD activation occurs in the kidneys involving a second hydroxylation reaction to generate the biologically active metabolite 1,25(OH)2-VD. Extrarenal 1α-hydroxylation has also been described to have an important role in autocrine and paracrine signaling. Vitamin D deficiency (VDD) has been in the spotlight as a major public healthcare issue with an estimated prevalence of more than a billion people worldwide. A...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
In conclusion, our results demonstrate a new mechanism involved in hypertension-associated proteinuria.
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Signal Transduction Source Type: research
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